Stents versus Coronary-Artery Bypass Grafting for Left Main Coronary Artery Disease

A cohort of patients who underwent stent implantation for unprotected left main coronary artery disease was compared with a propensity-matched cohort of patients who underwent coronary-artery bypass grafting. The risk of death and the composite outcome of death, Q-wave myocardial infarction, or stro...

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Veröffentlicht in:The New England journal of medicine 2008-04, Vol.358 (17), p.1781-1792
Hauptverfasser: Seung, Ki Bae, Park, Seong-Wook, Park, Duk-Woo, Park, Hun Sik, Park, Seung-Jung, Kim, Hyo-Soo, Kim, Pum Joon, Kim, Young-Hak, Lee, Seung-Whan, Lee, Cheol Whan, Hong, Myeong-Ki, Yun, Sung-Cheol, Gwon, Hyeon-Cheol, Jeong, Myung-Ho, Jang, Yangsoo, Seong, In-Whan, Ahn, Taehoon, Chae, In-Ho, Tahk, Seung-Jea, Chung, Wook-Sung
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container_end_page 1792
container_issue 17
container_start_page 1781
container_title The New England journal of medicine
container_volume 358
creator Seung, Ki Bae
Park, Seong-Wook
Park, Duk-Woo
Park, Hun Sik
Park, Seung-Jung
Kim, Hyo-Soo
Kim, Pum Joon
Kim, Young-Hak
Lee, Seung-Whan
Lee, Cheol Whan
Hong, Myeong-Ki
Yun, Sung-Cheol
Gwon, Hyeon-Cheol
Jeong, Myung-Ho
Jang, Yangsoo
Seong, In-Whan
Ahn, Taehoon
Chae, In-Ho
Tahk, Seung-Jea
Chung, Wook-Sung
description A cohort of patients who underwent stent implantation for unprotected left main coronary artery disease was compared with a propensity-matched cohort of patients who underwent coronary-artery bypass grafting. The risk of death and the composite outcome of death, Q-wave myocardial infarction, or stroke did not differ significantly between the two groups. The risk of target-vessel revascularization was higher in the group that received stents. The risk of death and the composite outcome of death, Q-wave myocardial infarction, or stroke did not differ significantly between the two groups. The risk of target-vessel revascularization was higher in the group that received stents. Significant narrowing of the left main coronary artery puts a patient at high risk, since it can jeopardize the entire myocardium of the left ventricle, and it has the worst prognosis of any form of coronary artery disease. 1 On the basis of clinical trials that show a survival benefit with bypass surgery as compared with medical treatment, 1 – 4 coronary-artery bypass grafting (CABG) has been considered standard therapy for patients with left main coronary artery disease and is recommended by current practice guidelines. 5 , 6 Because of concern about procedural risk and long-term durability, percutaneous coronary intervention (PCI) usually has been restricted . . .
doi_str_mv 10.1056/NEJMoa0801441
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Significant narrowing of the left main coronary artery puts a patient at high risk, since it can jeopardize the entire myocardium of the left ventricle, and it has the worst prognosis of any form of coronary artery disease. 1 On the basis of clinical trials that show a survival benefit with bypass surgery as compared with medical treatment, 1 – 4 coronary-artery bypass grafting (CABG) has been considered standard therapy for patients with left main coronary artery disease and is recommended by current practice guidelines. 5 , 6 Because of concern about procedural risk and long-term durability, percutaneous coronary intervention (PCI) usually has been restricted . . .</abstract><cop>Boston, MA</cop><pub>Massachusetts Medical Society</pub><pmid>18378517</pmid><doi>10.1056/NEJMoa0801441</doi><tpages>12</tpages><oa>free_for_read</oa></addata></record>
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source MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; New England Journal of Medicine
subjects Aged
Angioplasty, Balloon, Coronary
Biological and medical sciences
Cardiology. Vascular system
Cardiovascular disease
Cohort Studies
Coronary Artery Bypass
Coronary Disease - mortality
Coronary Disease - surgery
Coronary Disease - therapy
Coronary heart disease
Coronary vessels
Drug-Eluting Stents
Female
Follow-Up Studies
General aspects
Heart
Heart attacks
Humans
Kaplan-Meier Estimate
Male
Medical sciences
Middle Aged
Myocardial Infarction - epidemiology
Myocardial Revascularization
Risk Factors
Stents
Stroke - epidemiology
Treatment Outcome
title Stents versus Coronary-Artery Bypass Grafting for Left Main Coronary Artery Disease
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