The Role of Subtilisin-like Proprotein Convertases for Cleavage of the Measles Virus Fusion Glycoprotein in Different Cell Types

The fusion (F) glycoprotein gene of measles virus (MV) encodes a nonfusogenic precursor protein (F0) that is activated by cleavage into the F1and F2subunits during transport to the cell surface. The F protein of both the Edmonston strain and a wild-type MV was found to be cleaved in thetrans-Golgi c...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Virology (New York, N.Y.) N.Y.), 1998-12, Vol.252 (2), p.387-398
Hauptverfasser:	Bolt, Gert, Pedersen, Ib Rode
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma Carcinoma, Squamous Cell Furin Golgi Apparatus - enzymology Golgi Apparatus - virology Humans Kinetics Measles virus Measles virus - genetics Measles virus - physiology Recombinant Proteins - metabolism Reverse Transcriptase Polymerase Chain Reaction Serine Endopeptidases - genetics Serine Endopeptidases - metabolism Subtilisins - metabolism Tumor Cells, Cultured Viral Fusion Proteins - genetics Viral Fusion Proteins - metabolism Viral Plaque Assay
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!