Cellular biocompatibility and resistance to compression of macroporous β-tricalcium phosphate ceramics
The main problem for macroporous structures used as bone substitutes is their lower resistances when compared to that of cancellous bone. The present investigation aimed to improve the strength of ceramics with 65% porosities based on β-TCP. The initial mixtures were rendered plastic by addition of...
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| Veröffentlicht in: | Biomaterials 1998-12, Vol.19 (23), p.2147-2153 |
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| creator | Sous, M. Bareille, R. Rouais, F. Clément, D. Amédée, J. Dupuy, B. Baquey, Ch |
| description | The main problem for macroporous structures used as bone substitutes is their lower resistances when compared to that of cancellous bone. The present investigation aimed to improve the strength of ceramics with 65% porosities based on
β-TCP. The initial mixtures were rendered plastic by addition of non-ionic carbohydrate binders. Macropores were created using substances which were eliminated by heat. Mechanical tests indicated that the resistance of the ceramics depended more on the quantity than the nature of the binders. Porosity measurements were done with a mercury porosimeter, and cellular biocompatibility was evaluated by performing cellular attachment tests and observing the proliferation of differentiated cells. |
| doi_str_mv | 10.1016/S0142-9612(98)00118-5 |
| format | Article |
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β-TCP. The initial mixtures were rendered plastic by addition of non-ionic carbohydrate binders. Macropores were created using substances which were eliminated by heat. Mechanical tests indicated that the resistance of the ceramics depended more on the quantity than the nature of the binders. Porosity measurements were done with a mercury porosimeter, and cellular biocompatibility was evaluated by performing cellular attachment tests and observing the proliferation of differentiated cells.</description><identifier>ISSN: 0142-9612</identifier><identifier>EISSN: 1878-5905</identifier><identifier>DOI: 10.1016/S0142-9612(98)00118-5</identifier><identifier>PMID: 9884055</identifier><language>eng</language><publisher>Oxford: Elsevier Ltd</publisher><subject>Binding energy ; Biocompatibility ; Biocompatible Materials - chemistry ; Biological and medical sciences ; Bone ; Bone Marrow Cells - chemistry ; Calcium Phosphates - chemistry ; Cell Adhesion ; Cell culture ; Cell Division - physiology ; Cells, Cultured ; Ceramics ; Ceramics - chemistry ; Chemical Phenomena ; Chemistry, Physical ; Compressive Strength ; Cytocompatibility ; Humans ; Mechanical testing ; Medical sciences ; Microscopy, Electron, Scanning ; Osteoblasts - chemistry ; Porosity ; Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) ; Technology. Biomaterials. Equipments. Material. Instrumentation ; β-TCP</subject><ispartof>Biomaterials, 1998-12, Vol.19 (23), p.2147-2153</ispartof><rights>1998</rights><rights>1999 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c451t-8a029bc51fd581bee383102e3e476e2c4b88396bd13125c6ad51427b9ec718803</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0142961298001185$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1627151$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9884055$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sous, M.</creatorcontrib><creatorcontrib>Bareille, R.</creatorcontrib><creatorcontrib>Rouais, F.</creatorcontrib><creatorcontrib>Clément, D.</creatorcontrib><creatorcontrib>Amédée, J.</creatorcontrib><creatorcontrib>Dupuy, B.</creatorcontrib><creatorcontrib>Baquey, Ch</creatorcontrib><title>Cellular biocompatibility and resistance to compression of macroporous β-tricalcium phosphate ceramics</title><title>Biomaterials</title><addtitle>Biomaterials</addtitle><description>The main problem for macroporous structures used as bone substitutes is their lower resistances when compared to that of cancellous bone. The present investigation aimed to improve the strength of ceramics with 65% porosities based on
β-TCP. The initial mixtures were rendered plastic by addition of non-ionic carbohydrate binders. Macropores were created using substances which were eliminated by heat. Mechanical tests indicated that the resistance of the ceramics depended more on the quantity than the nature of the binders. Porosity measurements were done with a mercury porosimeter, and cellular biocompatibility was evaluated by performing cellular attachment tests and observing the proliferation of differentiated cells.</description><subject>Binding energy</subject><subject>Biocompatibility</subject><subject>Biocompatible Materials - chemistry</subject><subject>Biological and medical sciences</subject><subject>Bone</subject><subject>Bone Marrow Cells - chemistry</subject><subject>Calcium Phosphates - chemistry</subject><subject>Cell Adhesion</subject><subject>Cell culture</subject><subject>Cell Division - physiology</subject><subject>Cells, Cultured</subject><subject>Ceramics</subject><subject>Ceramics - chemistry</subject><subject>Chemical Phenomena</subject><subject>Chemistry, Physical</subject><subject>Compressive Strength</subject><subject>Cytocompatibility</subject><subject>Humans</subject><subject>Mechanical testing</subject><subject>Medical sciences</subject><subject>Microscopy, Electron, Scanning</subject><subject>Osteoblasts - chemistry</subject><subject>Porosity</subject><subject>Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)</subject><subject>Technology. Biomaterials. Equipments. Material. 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β-TCP. The initial mixtures were rendered plastic by addition of non-ionic carbohydrate binders. Macropores were created using substances which were eliminated by heat. Mechanical tests indicated that the resistance of the ceramics depended more on the quantity than the nature of the binders. Porosity measurements were done with a mercury porosimeter, and cellular biocompatibility was evaluated by performing cellular attachment tests and observing the proliferation of differentiated cells.</abstract><cop>Oxford</cop><pub>Elsevier Ltd</pub><pmid>9884055</pmid><doi>10.1016/S0142-9612(98)00118-5</doi><tpages>7</tpages></addata></record> |
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| ispartof | Biomaterials, 1998-12, Vol.19 (23), p.2147-2153 |
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| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Binding energy Biocompatibility Biocompatible Materials - chemistry Biological and medical sciences Bone Bone Marrow Cells - chemistry Calcium Phosphates - chemistry Cell Adhesion Cell culture Cell Division - physiology Cells, Cultured Ceramics Ceramics - chemistry Chemical Phenomena Chemistry, Physical Compressive Strength Cytocompatibility Humans Mechanical testing Medical sciences Microscopy, Electron, Scanning Osteoblasts - chemistry Porosity Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) Technology. Biomaterials. Equipments. Material. Instrumentation β-TCP |
| title | Cellular biocompatibility and resistance to compression of macroporous β-tricalcium phosphate ceramics |
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