Expression of Sonic hedgehog signaling pathway correlates with the tumorigenesis of intraductal papillary mucinous neoplasm of the pancreas

Sonic hedgehog (SHH) is frequently expressed in pre-cancerous lesions and carcinoma of the pancreas. A recent study revealed that its expression was higher in the intraductal papillary mucinous neoplasm (IPMN) of the pancreas than in the pancreatic carcinoma. However, the correlation between its sig...

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Veröffentlicht in:	Oncology reports 2008-05, Vol.19 (5), p.1185-1190
Hauptverfasser:	SATOH, Kennichi, KANNO, Atsushi, HAMADA, Shin, HIROTA, Morihisa, UMINO, Jun, MASAMUNE, Atsushi, EGAWA, Shinichi, MOTOI, Fuyuhiko, UNNO, Michiaki, SHIMOSEGAWA, Tooru
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma, Mucinous - metabolism Biological and medical sciences Carcinoma, Pancreatic Ductal - metabolism Gastroenterology. Liver. Pancreas. Abdomen Gene Expression Profiling Gene Expression Regulation, Neoplastic Hedgehog Proteins - metabolism Humans Immunohistochemistry - methods Liver. Biliary tract. Portal circulation. Exocrine pancreas Medical sciences Models, Statistical Pancreas - metabolism Pancreatic Neoplasms - metabolism Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - metabolism Signal Transduction Transcription Factors - biosynthesis Tumors Zinc Finger Protein GLI1
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