High periostin expression correlates with aggressiveness in papillary thyroid carcinomas

Periostin is a mesenchyme-specific gene product, which acts as an adhesion molecule during bone formation and supports osteoblastic cell line attachment and spreading. However, periostin expression is activated in a large variety of epithelial human tumors and correlates with their aggressiveness. K...

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Veröffentlicht in:	Journal of endocrinology 2008-05, Vol.197 (2), p.401-408
Hauptverfasser:	Puppin, Cinzia, Fabbro, Dora, Dima, Mariavittoria, Di Loreto, Carla, Puxeddu, Efisio, Filetti, Sebastiano, Russo, Diego, Damante, Giuseppe
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Carcinoma, Papillary - chemistry Carcinoma, Papillary - genetics Carcinoma, Papillary - pathology Cell Adhesion Molecules - analysis Cell Adhesion Molecules - genetics Cell Line, Tumor Endocrinopathies Humans Immunohistochemistry Malignant tumors Medical sciences Mutation Non tumoral diseases. Target tissue resistance. Benign neoplasms Proto-Oncogene Proteins B-raf - genetics Receptors, Thyrotropin - genetics Regular papers Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - analysis Thyroid Neoplasms - chemistry Thyroid Neoplasms - genetics Thyroid Neoplasms - pathology Thyroid. Thyroid axis (diseases)
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