Six-hour trimethoprim-sulfamethoxazole–graded challenge in HIV-infected patients

Background: Hypersensitivity reactions to trimethoprim-sulfamethoxazole (TMP-SMX) are very common in HIV-infected patients, leading to drug discontinuation. However, it is the drug of choice as prophylaxis for Pneumocystis carinii pneumonia. Objectives: We sought to determine the safety and long-ter...

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Veröffentlicht in:	Journal of allergy and clinical immunology 1998-12, Vol.102 (6), p.1033-1036
Hauptverfasser:	Demoly, Pascal, Messaad, Djamel, Sahla, Hocine, Fabre, Jacqueline, Faucherre, Vincent, André, Pascal, Reynes, Jacques, Godard, Philippe, Bousquet, Jean
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Adult AIDS/HIV Biological and medical sciences cotrimoxazole desensitization Drug Administration Schedule Drug Hypersensitivity - blood Drug Hypersensitivity - immunology Drug Hypersensitivity - prevention & control Female graded challenge HIV HIV Infections - drug therapy HIV Infections - immunology Human immunodeficiency virus Humans hypersensitivity Immunopathology Immunotherapy (general aspects) Male Medical sciences Pneumocystis carinii Prospective Studies tolerance Trimethoprim, Sulfamethoxazole Drug Combination - administration & dosage Trimethoprim-sulfamethoxazole
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