Complementary DNA Sequence of Chicken Thyroid-Stimulating Hormone (TSH) β Subunit

Chicken TSH β subunit cDNA was cloned and sequenced. The cDNA encodes a putative signal peptide and a mature protein consisting of 20 and 114 amino acids, respectively. The amino acid sequence of chicken TSH β subunit is highly conserved (98.5%) between chicken and Japanese quail, whereas it has a l...

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Veröffentlicht in:Endocrine Journal 1998, Vol.45(4), pp.591-594
Hauptverfasser: KATO, YUKIO, KATO, TAKAKO, TOMIZAWA, KYOKO, KAMIYOSHI, MICHIHARU, IWASAWA, ATSUSHI
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Sprache:eng
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Zusammenfassung:Chicken TSH β subunit cDNA was cloned and sequenced. The cDNA encodes a putative signal peptide and a mature protein consisting of 20 and 114 amino acids, respectively. The amino acid sequence of chicken TSH β subunit is highly conserved (98.5%) between chicken and Japanese quail, whereas it has a low homology between chicken and mammals (67-69%), an amphibian (58%) and fish (40-49%). Structural characteristics of TSH β subunits of avian species are discussed in comparison with those of non-avian vertebrates.
ISSN:0918-8959
1348-4540
DOI:10.1507/endocrj.45.591