Nitric oxide enhances thyroid peroxidase activity in primary human thyrocytes

Recent studies have demonstrated the production of the multi-functional messenger molecule nitric oxide (NO) by the thyroid gland. To examine a possible role for NO in thyroid function, we studied the acute and chronic effect of NO donors on thyroid peroxidase (TPO) activity in monolayer cultures of...

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Veröffentlicht in:	Life sciences (1973) 1998, Vol.63 (26), p.PL373-PL380
Hauptverfasser:	Millatt, Lesley J., Johnstone, Alan P., Whitley, Guy StJ
Format:	Artikel
Sprache:	eng
Schlagworte:	Cells, Cultured Glutathione - analogs & derivatives Glutathione - pharmacology Humans Iodide Peroxidase - metabolism nitric oxide Nitric Oxide - physiology Nitric Oxide Donors - pharmacology Nitric Oxide Synthase - metabolism Nitroprusside - pharmacology Nitroso Compounds - pharmacology S-Nitrosoglutathione thyrocyte Thyroid Gland - cytology Thyroid Gland - enzymology thyroid peroxidase
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