Numerical study on the effect of steady axial flow development in the human aorta on local shear stresses in abdominal aortic branches
The three-dimensional flow through a rigid model of the human abdominal aorta complete with iliac and renal arteries was predicted numerically using the steady-state Navier–Stokes equations for an incompressible, Newtonian fluid. The model adapted for our purposes was determined from data obtained f...
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Veröffentlicht in: | Journal of biomechanics 1998-11, Vol.31 (11), p.995-1007 |
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creator | Shipkowitz, Tanya Rodgers, V.G.J. Frazin, Lee J. Chandran, K.B. |
description | The three-dimensional flow through a rigid model of the human abdominal aorta complete with iliac and renal arteries was predicted numerically using the steady-state Navier–Stokes equations for an incompressible, Newtonian fluid. The model adapted for our purposes was determined from data obtained from cine-CT images taken of a glass chamber that was constructed based on anatomical averages. The iliac arteries had a bifurcation angle of approximately 35° and a branch-to-trunk area ratio of 1.27, whereas the renal arteries had left and right branch angles of 40° and an area ratio of 0.73. The numerical tool FLOW3D (AEA Industrial Technology, Oxfordshire, UK) utilized body-fitted coordinates and a finite volume discretization procedure. Purely axial velocity profiles were introduced at the entrance of the model for a range of cardiac outputs. The four-branch numerical model developed for this investigation produced flow and shear conditions comparable to those found in other reported works. The total wall shear stress distribution in the iliac and renal arteries followed standard trends, with maximum shear stresses occurring in the apex region and lower shear stresses occurring along the lateral walls. Shear stresses and flow rate ratios in the downstream arteries were more effected by inlet
Re than the upstream arteries. These results will be used to compare further simulations which take into effect the rotational component of flow which is present in the aortic arch. |
doi_str_mv | 10.1016/S0021-9290(98)00103-1 |
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Re than the upstream arteries. These results will be used to compare further simulations which take into effect the rotational component of flow which is present in the aortic arch.</description><identifier>ISSN: 0021-9290</identifier><identifier>EISSN: 1873-2380</identifier><identifier>DOI: 10.1016/S0021-9290(98)00103-1</identifier><identifier>PMID: 9880056</identifier><language>eng</language><publisher>United States: Elsevier Ltd</publisher><subject>Abdominal aorta ; Aorta, Abdominal - physiology ; Aortic bifurcation ; Atherosclerosis ; Axial flow ; Blood vessels ; Computer simulation ; Computerized tomography ; Finite volume method ; Hemodynamics ; Humans ; Iliac Artery - physiology ; Medical imaging ; Models, Anatomic ; Models, Cardiovascular ; Navier Stokes equations ; Newtonian flow ; Numerical Analysis, Computer-Assisted ; Numerical model ; Renal arteries ; Renal Artery - physiology ; Shear stress ; Stress, Mechanical ; Tomography, X-Ray Computed ; Wall shear stress</subject><ispartof>Journal of biomechanics, 1998-11, Vol.31 (11), p.995-1007</ispartof><rights>1998 Elsevier Science Ltd</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c391t-16628a939d2445ea5d499eaae27d3fc40630a502e73fd584be04b5221244bd883</citedby><cites>FETCH-LOGICAL-c391t-16628a939d2445ea5d499eaae27d3fc40630a502e73fd584be04b5221244bd883</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/S0021-9290(98)00103-1$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/9880056$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Shipkowitz, Tanya</creatorcontrib><creatorcontrib>Rodgers, V.G.J.</creatorcontrib><creatorcontrib>Frazin, Lee J.</creatorcontrib><creatorcontrib>Chandran, K.B.</creatorcontrib><title>Numerical study on the effect of steady axial flow development in the human aorta on local shear stresses in abdominal aortic branches</title><title>Journal of biomechanics</title><addtitle>J Biomech</addtitle><description>The three-dimensional flow through a rigid model of the human abdominal aorta complete with iliac and renal arteries was predicted numerically using the steady-state Navier–Stokes equations for an incompressible, Newtonian fluid. The model adapted for our purposes was determined from data obtained from cine-CT images taken of a glass chamber that was constructed based on anatomical averages. The iliac arteries had a bifurcation angle of approximately 35° and a branch-to-trunk area ratio of 1.27, whereas the renal arteries had left and right branch angles of 40° and an area ratio of 0.73. The numerical tool FLOW3D (AEA Industrial Technology, Oxfordshire, UK) utilized body-fitted coordinates and a finite volume discretization procedure. Purely axial velocity profiles were introduced at the entrance of the model for a range of cardiac outputs. The four-branch numerical model developed for this investigation produced flow and shear conditions comparable to those found in other reported works. The total wall shear stress distribution in the iliac and renal arteries followed standard trends, with maximum shear stresses occurring in the apex region and lower shear stresses occurring along the lateral walls. Shear stresses and flow rate ratios in the downstream arteries were more effected by inlet
Re than the upstream arteries. These results will be used to compare further simulations which take into effect the rotational component of flow which is present in the aortic arch.</description><subject>Abdominal aorta</subject><subject>Aorta, Abdominal - physiology</subject><subject>Aortic bifurcation</subject><subject>Atherosclerosis</subject><subject>Axial flow</subject><subject>Blood vessels</subject><subject>Computer simulation</subject><subject>Computerized tomography</subject><subject>Finite volume method</subject><subject>Hemodynamics</subject><subject>Humans</subject><subject>Iliac Artery - physiology</subject><subject>Medical imaging</subject><subject>Models, Anatomic</subject><subject>Models, Cardiovascular</subject><subject>Navier Stokes equations</subject><subject>Newtonian flow</subject><subject>Numerical Analysis, Computer-Assisted</subject><subject>Numerical model</subject><subject>Renal arteries</subject><subject>Renal Artery - physiology</subject><subject>Shear stress</subject><subject>Stress, Mechanical</subject><subject>Tomography, X-Ray Computed</subject><subject>Wall shear stress</subject><issn>0021-9290</issn><issn>1873-2380</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1998</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkc1u1DAURi1EVYbCI1TyCtFFyvVPEnuFUEUBqYJFy9py7BuNURIPdlLaF-hz48yMuu3K0r3n-67kQ8g5g0sGrPl0C8BZpbmGj1pdADAQFXtFNky1ouJCwWuyeUbekLc5_wGAVrb6lJxqpQDqZkOefi4jpuDsQPO8-EcaJzpvkWLfo5tp7MsYbZnbh1CYfoj_qMd7HOJuxGmm4YBvl9FO1MY027VhiPvCLdpU8glzxryitvNxDFPZrWhwtEt2clvM78hJb4eM74_vGfl9_fXu6nt18-vbj6svN5UTms0VaxqurBbacylrtLWXWqO1yFsveiehEWBr4NiK3tdKdgiyqzlnBe-8UuKMfDj07lL8u2CezRiyw2GwE8Ylm0YzplXNXwQ5E1pKJQtYH0CXYs4Je7NLYbTp0TAwqyizF2VWC0YrsxdlWMmdHw8s3Yj-OXU0U_afD3ss33EfMJnsAk4OfUjFjPExvHDhP-CJo68</recordid><startdate>19981101</startdate><enddate>19981101</enddate><creator>Shipkowitz, Tanya</creator><creator>Rodgers, V.G.J.</creator><creator>Frazin, Lee J.</creator><creator>Chandran, K.B.</creator><general>Elsevier Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19981101</creationdate><title>Numerical study on the effect of steady axial flow development in the human aorta on local shear stresses in abdominal aortic branches</title><author>Shipkowitz, Tanya ; Rodgers, V.G.J. ; Frazin, Lee J. ; Chandran, K.B.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c391t-16628a939d2445ea5d499eaae27d3fc40630a502e73fd584be04b5221244bd883</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1998</creationdate><topic>Abdominal aorta</topic><topic>Aorta, Abdominal - physiology</topic><topic>Aortic bifurcation</topic><topic>Atherosclerosis</topic><topic>Axial flow</topic><topic>Blood vessels</topic><topic>Computer simulation</topic><topic>Computerized tomography</topic><topic>Finite volume method</topic><topic>Hemodynamics</topic><topic>Humans</topic><topic>Iliac Artery - physiology</topic><topic>Medical imaging</topic><topic>Models, Anatomic</topic><topic>Models, Cardiovascular</topic><topic>Navier Stokes equations</topic><topic>Newtonian flow</topic><topic>Numerical Analysis, Computer-Assisted</topic><topic>Numerical model</topic><topic>Renal arteries</topic><topic>Renal Artery - physiology</topic><topic>Shear stress</topic><topic>Stress, Mechanical</topic><topic>Tomography, X-Ray Computed</topic><topic>Wall shear stress</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Shipkowitz, Tanya</creatorcontrib><creatorcontrib>Rodgers, V.G.J.</creatorcontrib><creatorcontrib>Frazin, Lee J.</creatorcontrib><creatorcontrib>Chandran, K.B.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of biomechanics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Shipkowitz, Tanya</au><au>Rodgers, V.G.J.</au><au>Frazin, Lee J.</au><au>Chandran, K.B.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Numerical study on the effect of steady axial flow development in the human aorta on local shear stresses in abdominal aortic branches</atitle><jtitle>Journal of biomechanics</jtitle><addtitle>J Biomech</addtitle><date>1998-11-01</date><risdate>1998</risdate><volume>31</volume><issue>11</issue><spage>995</spage><epage>1007</epage><pages>995-1007</pages><issn>0021-9290</issn><eissn>1873-2380</eissn><abstract>The three-dimensional flow through a rigid model of the human abdominal aorta complete with iliac and renal arteries was predicted numerically using the steady-state Navier–Stokes equations for an incompressible, Newtonian fluid. The model adapted for our purposes was determined from data obtained from cine-CT images taken of a glass chamber that was constructed based on anatomical averages. The iliac arteries had a bifurcation angle of approximately 35° and a branch-to-trunk area ratio of 1.27, whereas the renal arteries had left and right branch angles of 40° and an area ratio of 0.73. The numerical tool FLOW3D (AEA Industrial Technology, Oxfordshire, UK) utilized body-fitted coordinates and a finite volume discretization procedure. Purely axial velocity profiles were introduced at the entrance of the model for a range of cardiac outputs. The four-branch numerical model developed for this investigation produced flow and shear conditions comparable to those found in other reported works. The total wall shear stress distribution in the iliac and renal arteries followed standard trends, with maximum shear stresses occurring in the apex region and lower shear stresses occurring along the lateral walls. Shear stresses and flow rate ratios in the downstream arteries were more effected by inlet
Re than the upstream arteries. These results will be used to compare further simulations which take into effect the rotational component of flow which is present in the aortic arch.</abstract><cop>United States</cop><pub>Elsevier Ltd</pub><pmid>9880056</pmid><doi>10.1016/S0021-9290(98)00103-1</doi><tpages>13</tpages></addata></record> |
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subjects | Abdominal aorta Aorta, Abdominal - physiology Aortic bifurcation Atherosclerosis Axial flow Blood vessels Computer simulation Computerized tomography Finite volume method Hemodynamics Humans Iliac Artery - physiology Medical imaging Models, Anatomic Models, Cardiovascular Navier Stokes equations Newtonian flow Numerical Analysis, Computer-Assisted Numerical model Renal arteries Renal Artery - physiology Shear stress Stress, Mechanical Tomography, X-Ray Computed Wall shear stress |
title | Numerical study on the effect of steady axial flow development in the human aorta on local shear stresses in abdominal aortic branches |
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