Effect of Alendronate on Risk of Fracture in Women With Low Bone Density but Without Vertebral Fractures: Results From the Fracture Intervention Trial

CONTEXT.— Alendronate sodium reduces fracture risk in postmenopausal women who have vertebral fractures, but its effects on fracture risk have not been studied for women without vertebral fractures. OBJECTIVE.— To test the hypothesis that 4 years of alendronate would decrease the risk of clinical an...

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Veröffentlicht in:	JAMA : the journal of the American Medical Association 1998-12, Vol.280 (24), p.2077-2082
Hauptverfasser:	Cummings, Steven R, Black, Dennis M, Thompson, Desmond E, Applegate, William B, Barrett-Connor, Elizabeth, Musliner, Thomas A, Palermo, Lisa, Prineas, Ronald, Rubin, Susan M, Scott, Jean C, Vogt, Thomas, Wallace, Robert, Yates, A. John, LaCroix, Andrea Z, for the Fracture Intervention Trial Research Group
Format:	Artikel
Sprache:	eng
Schlagworte:	Absorptiometry, Photon Aged Aged, 80 and over Alendronate - therapeutic use alendronic acid Biological and medical sciences bisphosphonates Bone Density Bones Bones, joints and connective tissue. Antiinflammatory agents Calcium - administration & dosage Cholecalciferol - administration & dosage Dietary Supplements Female Femur Neck - diagnostic imaging Femur Neck - pathology Fractures Fractures, Bone - prevention & control Health risk assessment Humans Medical sciences Middle Aged Osteoporosis, Postmenopausal - drug therapy Pharmacology. Drug treatments Risk Spinal Fractures - prevention & control Spine - diagnostic imaging Spine - pathology Women
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