Low levels of ionic mercury modulate protein tyrosine phosphorylation in lymphocytes

The ability of ionic mercury to induce protein tyrosine phosphorylation in mouse spleen cells and in the mouse WEHI-231 B-cell lymphoma was investigated. We have confirmed previous studies which showed that exposure to high levels (several hundred μM) of mercury lead to very large increases in the l...

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Veröffentlicht in:	International journal of immunopharmacology 1998-12, Vol.20 (12), p.697-707
Hauptverfasser:	Rosenspire, A.j., Bodepudi, S., Mathews, M., Jr, M.J.McCabe
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals B-Lymphocytes - drug effects B-Lymphocytes - metabolism Biological and medical sciences Cations, Divalent Chelating Agents - pharmacology Chemical and industrial products toxicology. Toxic occupational diseases Ethylmaleimide - pharmacology Lymphocyte Lymphoma, B-Cell Medical sciences Mercury Mercury - metabolism Mercury - pharmacology Metals and various inorganic compounds Mice Mice, Inbred BALB C Mice, Inbred DBA Penicillamine - pharmacology Phosphoproteins - metabolism Phosphorylation - drug effects Phosphotyrosine - metabolism Protein tyrosine phosphorylation Signal transduction Spleen - cytology Spleen - drug effects Spleen - metabolism Sulfhydryl Reagents - pharmacology Toxicology Tumor Cells, Cultured
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