Prospective study of homocysteine and MTHFR 677TT genotype and risk for venous thrombosis in a general population – results from the HUNT 2 study

Summary This case‐cohort designed study prospectively investigated whether elevated homocysteine levels measured in blood samples drawn before the event and methylenetetrahydrofolate reductase (MTHFR) gene polymorphism (MTHFR C677T) were associated with subsequent first venous thrombosis (VT) in a g...

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Veröffentlicht in:	British journal of haematology 2008-05, Vol.141 (4), p.529-535
Hauptverfasser:	Næss, Inger Anne, Christiansen, Sverre C., Romundstad, Pål R., Cannegieter, Suzanne C., Blom, Henk J., Rosendaal, Frits R., Hammerstrøm, Jens
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Biological and medical sciences Biomarkers - blood Blood and lymphatic vessels Cardiology. Vascular system deep vein thrombosis Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous Epidemiologic Methods Female Genetic Predisposition to Disease Genotype Hematologic and hematopoietic diseases homocysteine Homocysteine - blood Humans Male Medical sciences Methylenetetrahydrofolate Reductase (NADPH2) - genetics Middle Aged MTHFR 677TT genotype pulmonary embolism Pulmonary Embolism - blood Pulmonary Embolism - genetics venous thrombosis Venous Thrombosis - blood Venous Thrombosis - genetics
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