T cells in Cardiac Allograft Vasculopathy Are Skewed to Memory Th‐1 Cells in the Presence of a Distinct Th‐2 Population

Cardiac allograft vasculopathy (CAV) in heart transplantation (HTx) patients remains the major complication for long‐term survival, due to concentric neointima hyperplasia induced by infiltrating mononuclear cells (MNC). Previously, we showed that activated memory T‐helper‐1 (Th‐1) cells are the maj...

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Veröffentlicht in:	American journal of transplantation 2008-05, Vol.8 (5), p.1040-1050
Hauptverfasser:	Hagemeijer, M. C., Van Oosterhout, M. F. M., Van Wichen, D. F., Van Kuik, J., Siera‐de Koning, E., Gmelig Meyling, F. H. J., Schipper, M. E. I., De Jonge, N., De Weger, R. A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Allograft arteriopathy alloreactive T cells Biological and medical sciences Blood and lymphatic vessels Cardiology. Vascular system chronic allograft rejection coronary artery disease Coronary heart disease Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous Heart Heart Transplantation - immunology Heart Transplantation - pathology Humans Immunologic Memory Medical sciences Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases T-Lymphocytes - immunology Th1 Cells - immunology Th2 Cells - immunology Transplantation, Homologous - immunology Transplantation, Homologous - pathology vasculopathy
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