Immunological mechanisms in the pathogenesis of diabetic retinopathy

There is an accumulating body of evidence that immunological mechanisms play a prominent role in the pathogenesis of diabetic retinopathy (DR), which is characterized by many features typical of inflammation. The upregulation of cytokines and other inflammatory mediators leading to persistent low-gr...

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Veröffentlicht in:	Seminars in immunopathology 2008-04, Vol.30 (2), p.65-84
Hauptverfasser:	Adamis, Anthony P., Berman, Adrienne J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenal Cortex Hormones - therapeutic use Anti-Inflammatory Agents, Non-Steroidal - therapeutic use Biomedical and Life Sciences Biomedicine Blood vessels Clinical Trials as Topic Diabetes Diabetic retinopathy Diabetic Retinopathy - drug therapy Diabetic Retinopathy - immunology Edema Humans Immune system Immunology Inflammation Inflammation - immunology Internal Medicine Kinases Leukocytes Ligands Neovascularization, Pathologic - immunology Neutrophils Pathogenesis Pathophysiology Permeability Retina - immunology Retinal Vessels - immunology Retinal Vessels - physiopathology Review Vascular Endothelial Growth Factor A - metabolism
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