Host Polymorphisms in Interleukin 4, Complement Factor H, and C-Reactive Protein Associated with Nasal Carriage of Staphylococcus aureus and Occurrence of Boils

BackgroundStaphylococcus aureus is capable of persistently colonizing the vestibulum nasi. We hypothesized that polymorphisms in host inflammatory response genes and genetic variation in S. aureus contribute to susceptibility to S. aureus carriage and infection MethodsThe prevalence of persistent na...

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Veröffentlicht in:	The Journal of infectious diseases 2008-05, Vol.197 (9), p.1244-1253
Hauptverfasser:	Emonts, Marieke, Uitterlinden, André G., Nouwen, Jan L., Kardys, Isabella, de Maat, Moniek P. M., Melles, Damian C., Witteman, Jacqueline, de Jong, Paulus T. V. M., Verbrugh, Henri A., Hofman, Albert, Hermans, Peter W. M., van Belkum, Alex
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Bacteria C-Reactive Protein - genetics C-Reactive Protein - metabolism Carrier State Cohort Studies Complement Factor H - genetics Complement Factor H - metabolism DNA - genetics DNA - isolation & purification Eczema Furunculosis Furunculosis - epidemiology Genetic variation Genotypes Haplotypes Humans Infections Interleukin-4 - genetics Interleukin-4 - metabolism Mucins Nose Polymorphism, Genetic Staphylococcal Infections - epidemiology Staphylococcal Infections - genetics Staphylococcal Infections - microbiology Staphylococcus Staphylococcus aureus Staphylococcus aureus - isolation & purification
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