Multibacillary leprosy: lesions with macrophages positive for S100 protein and dendritic cells positive for Factor 13a

In the defense against Mycobacterium leprae, macrophages play an essential part in the mechanism of bacterial lysis but require the presence of cytokines such as interleukin 2 and gamma interferon from lymphocytes in order to effectively kill the organisms in any number. While there have been many s...

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