Hypoxic and hyperoxic effect on blood phosphodiesterase activity in young and old rats

In the present work we describe phosphodiesterase (PDEs) activity in the blood of young and old rats kept under hypoxic or hyperoxic normobaric conditions in order to correlate the age-change response with PDE levels and oxygen supply. PDE is important in the process of energy supply and as a modula...

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Veröffentlicht in:	Life sciences (1973) 1998, Vol.63 (25), p.PL349-PL353
Hauptverfasser:	Spoto, Giuseppe, Di Giulio, Camillo, Contento, Alessandro, Di Stilio, Mauro
Format:	Artikel
Sprache:	eng
Schlagworte:	3',5'-Cyclic-AMP Phosphodiesterases - blood 3',5'-Cyclic-GMP Phosphodiesterases - blood age Aging - metabolism Animals blood hyperoxia Hyperoxia - enzymology hypoxia Hypoxia - enzymology Oxidative Stress - physiology phosphodiesterase Phosphoric Diester Hydrolases - blood Rats Rats, Wistar Reactive Oxygen Species - metabolism Space life sciences
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