Seroepidemiology of Hepatitis B in Greek Children 6 Years After the Implementation of Universal Vaccination
The seroepidemiology of hepatitis B in children living in Greece 6 years post-implementation of universal infant immunization (1998) was studied. We collected 90–100 sera/year of age, stratified by geographic region. The prevalence of HbsAg(+) was 0.6% (95% CI 0.3–1.3) whereas 4.5% (95% CI 3.4–5.9%)...
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| Veröffentlicht in: | Infection 2008-04, Vol.36 (2), p.135-139 |
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| container_title | Infection |
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| creator | Papaevangelou, V. Hadjichristodoulou, C. Cassimos, D. C. Pantelaki, K. Tzivaras, A. Hatzimichael, A. Theodoridou, M. |
| description | The seroepidemiology of hepatitis B in children living in Greece 6 years post-implementation of universal infant immunization (1998) was studied. We collected 90–100 sera/year of age, stratified by geographic region. The prevalence of HbsAg(+) was 0.6% (95% CI 0.3–1.3) whereas 4.5% (95% CI 3.4–5.9%) of children over 12 months of age had evidence of past HBV infection. A significant decline in the prevalence of past infection between children born before and after 1998 (5.5% vs 2.9%; RR = 1.9, 95% CI 1.03–3.5) was noted. Conversely, the prevalence of past HBV infection did not change significantly among immigrant children. Reinforcement of early vaccination of immigrant population is necessary. |
| doi_str_mv | 10.1007/s15010-007-7096-6 |
| format | Article |
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Reinforcement of early vaccination of immigrant population is necessary.</description><identifier>ISSN: 0300-8126</identifier><identifier>EISSN: 1439-0973</identifier><identifier>EISSN: 1439-0972</identifier><identifier>DOI: 10.1007/s15010-007-7096-6</identifier><identifier>PMID: 18231718</identifier><language>eng</language><publisher>Munich: Urban & Vogel</publisher><subject>Adolescent ; Analysis of Variance ; Chi-Square Distribution ; Child ; Child, Preschool ; Clinical and Epidemiological Study ; Family Medicine ; General Practice ; Greece - epidemiology ; Hepatitis ; Hepatitis B - epidemiology ; Hepatitis B - prevention & control ; Hepatitis B Antibodies - blood ; Hepatitis B Core Antigens - immunology ; Hepatitis B Surface Antigens - analysis ; Hepatitis B Vaccines - administration & dosage ; Hepatitis B Vaccines - immunology ; Hepatitis B virus ; Hepatitis B virus - immunology ; Humans ; Immunization ; Infant ; Infant, Newborn ; Infectious Diseases ; Internal Medicine ; Longitudinal Studies ; Mass Vaccination ; Medicine ; Medicine & Public Health ; Seroepidemiologic Studies ; Vaccines</subject><ispartof>Infection, 2008-04, Vol.36 (2), p.135-139</ispartof><rights>Urban & Vogel München 2008</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c400t-c08f76bd0a88fa54809d0e2d0ef37b80ede911ee1c52d97831f66871f24582903</citedby><cites>FETCH-LOGICAL-c400t-c08f76bd0a88fa54809d0e2d0ef37b80ede911ee1c52d97831f66871f24582903</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s15010-007-7096-6$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s15010-007-7096-6$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27903,27904,41467,42536,51297</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18231718$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Papaevangelou, V.</creatorcontrib><creatorcontrib>Hadjichristodoulou, C.</creatorcontrib><creatorcontrib>Cassimos, D. 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Conversely, the prevalence of past HBV infection did not change significantly among immigrant children. Reinforcement of early vaccination of immigrant population is necessary.</description><subject>Adolescent</subject><subject>Analysis of Variance</subject><subject>Chi-Square Distribution</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Clinical and Epidemiological Study</subject><subject>Family Medicine</subject><subject>General Practice</subject><subject>Greece - epidemiology</subject><subject>Hepatitis</subject><subject>Hepatitis B - epidemiology</subject><subject>Hepatitis B - prevention & control</subject><subject>Hepatitis B Antibodies - blood</subject><subject>Hepatitis B Core Antigens - immunology</subject><subject>Hepatitis B Surface Antigens - analysis</subject><subject>Hepatitis B Vaccines - administration & dosage</subject><subject>Hepatitis B Vaccines - immunology</subject><subject>Hepatitis B virus</subject><subject>Hepatitis B virus - immunology</subject><subject>Humans</subject><subject>Immunization</subject><subject>Infant</subject><subject>Infant, Newborn</subject><subject>Infectious Diseases</subject><subject>Internal Medicine</subject><subject>Longitudinal Studies</subject><subject>Mass Vaccination</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Seroepidemiologic Studies</subject><subject>Vaccines</subject><issn>0300-8126</issn><issn>1439-0973</issn><issn>1439-0972</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNqFkU1rFTEUhoMo9lr9AW4kuHA3ek4yk49lvWhbKLjQCq7C3JmTNu1MMiZzhf57Z7wXCoK4CDlwnvcJ4WXsNcJ7BNAfCjaAUC1jpcGqSj1hG6ylrcBq-ZRtQAJUBoU6YS9KuQOAxtb6OTtBIyRqNBt2_5Vyoin0NIY0pJsHnjy_oKmdwxwK_8hD5OeZ6J5vb8PQZ4pc8R_U5sLP_EyZz7fEL8dpoJHivKRSXA3XMfyiXNqBf2-7LsQ_i5fsmW-HQq-O9ym7_vzp2_aiuvpyfrk9u6q6GmCuOjBeq10PrTG-bWoDtgcSy_FS7wxQTxaRCLtG9FYbiV4po9GLujHCgjxl7w7eKaefeyqzG0PpaBjaSGlfnLIIstHqv6AAo-sGxQK-_Qu8S_scl084gY1CWdvVhgeoy6mUTN5NOYxtfnAIbu3LHfpy67j25dbMm6N4vxupf0wcC1oAcQDKsoo3lB9f_rf1N8Sgn0I</recordid><startdate>20080401</startdate><enddate>20080401</enddate><creator>Papaevangelou, V.</creator><creator>Hadjichristodoulou, C.</creator><creator>Cassimos, D. 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A significant decline in the prevalence of past infection between children born before and after 1998 (5.5% vs 2.9%; RR = 1.9, 95% CI 1.03–3.5) was noted. Conversely, the prevalence of past HBV infection did not change significantly among immigrant children. Reinforcement of early vaccination of immigrant population is necessary.</abstract><cop>Munich</cop><pub>Urban & Vogel</pub><pmid>18231718</pmid><doi>10.1007/s15010-007-7096-6</doi><tpages>5</tpages></addata></record> |
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| ispartof | Infection, 2008-04, Vol.36 (2), p.135-139 |
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| subjects | Adolescent Analysis of Variance Chi-Square Distribution Child Child, Preschool Clinical and Epidemiological Study Family Medicine General Practice Greece - epidemiology Hepatitis Hepatitis B - epidemiology Hepatitis B - prevention & control Hepatitis B Antibodies - blood Hepatitis B Core Antigens - immunology Hepatitis B Surface Antigens - analysis Hepatitis B Vaccines - administration & dosage Hepatitis B Vaccines - immunology Hepatitis B virus Hepatitis B virus - immunology Humans Immunization Infant Infant, Newborn Infectious Diseases Internal Medicine Longitudinal Studies Mass Vaccination Medicine Medicine & Public Health Seroepidemiologic Studies Vaccines |
| title | Seroepidemiology of Hepatitis B in Greek Children 6 Years After the Implementation of Universal Vaccination |
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