Characterization of cytoplasmic secretory granules (PSG), in prostatic epithelium and their transformation-induced loss in dysplasia and adenocarcinoma

Cytoplasmic clarity is a histological feature of normal prostatic secretory cells, but in this study, tissue fixation in strong (>2.5%) glutaraldehyde dramatically altered cytological staining. Secretory cytoplasm appeared red and granular on routine stains because of myriad intensely staining eo...

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Veröffentlicht in:	Human pathology 1998-12, Vol.29 (12), p.1488-1494
Hauptverfasser:	Cohen, Ronald J, McNeal, John E, Edgar, Stephen G, Robertson, Terry, Dawkins, Hugh J.S
Format:	Artikel
Sprache:	eng
Schlagworte:	Acid Phosphatase - metabolism Adenocarcinoma, Clear Cell - metabolism Adenocarcinoma, Clear Cell - pathology Biological and medical sciences Cell Transformation, Neoplastic - pathology clear cytoplasm Cytoplasmic Granules - metabolism Cytoplasmic Granules - ultrastructure Epithelial Cells - metabolism Epithelial Cells - pathology granules Humans Immunoenzyme Techniques Male Medical sciences Nephrology. Urinary tract diseases Precancerous Conditions - metabolism Precancerous Conditions - pathology prostate Prostate - metabolism Prostate - pathology Prostate-Specific Antigen - metabolism Prostatic Neoplasms - metabolism Prostatic Neoplasms - pathology protease secretion secretory Tumors of the urinary system Urinary tract. Prostate gland
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