Manufacturing and microscopical characterisation of polyurethane nerve guidance channel featuring a highly smooth internal surface

The present study demonstrates the possibility of manufacturing polyurethane [ChronoFlex ® (CF)] nerve guidance channels (NGCs) featuring a highly smooth internal surface. Comparative SEM and AFM observations prove marked differences between the internal surface microgeometry of Silastic and CF chan...

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Veröffentlicht in:Biomaterials 1998-11, Vol.19 (21), p.1919-1924
Hauptverfasser: Soldani, G., Varelli, G., Minnocci, A., Dario, P.
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container_end_page 1924
container_issue 21
container_start_page 1919
container_title Biomaterials
container_volume 19
creator Soldani, G.
Varelli, G.
Minnocci, A.
Dario, P.
description The present study demonstrates the possibility of manufacturing polyurethane [ChronoFlex ® (CF)] nerve guidance channels (NGCs) featuring a highly smooth internal surface. Comparative SEM and AFM observations prove marked differences between the internal surface microgeometry of Silastic and CF channels. SEM of CF samples shows a surface with no detectable roughness, while Silastic channels show transversal rows along the entire surface. AFM digital image of Silastic samples show a surface with a rough microgeometry defined by a tridimensional pattern with peaks up to 1400 nm. AFM digital image of CF samples show, indeed, an essentially flat microgeometry with the highest level at 545 nm. These preliminary results suggest that the association of an innovative sequential deposition manufacturing technique with the new CF polyurethane may produce NGCs with a smoother surface microgeometry, in comparison to NGCs obtained from commercial Silastic tubes.
doi_str_mv 10.1016/S0142-9612(98)00085-4
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These preliminary results suggest that the association of an innovative sequential deposition manufacturing technique with the new CF polyurethane may produce NGCs with a smoother surface microgeometry, in comparison to NGCs obtained from commercial Silastic tubes.</description><subject>AFM</subject><subject>Atomic force microscopy</subject><subject>Biocompatible Materials - chemistry</subject><subject>Biological and medical sciences</subject><subject>Biopolymers</subject><subject>Grafts</subject><subject>Guided Tissue Regeneration - instrumentation</subject><subject>Guided Tissue Regeneration - methods</subject><subject>Image processing</subject><subject>Medical sciences</subject><subject>Microgeometry</subject><subject>Microscopy, Atomic Force</subject><subject>Microscopy, Electron, Scanning</subject><subject>Nerve guidance channels</subject><subject>Nerve Regeneration</subject><subject>Polyurethanes</subject><subject>Polyurethanes - chemistry</subject><subject>Radiotherapy. 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source MEDLINE; Elsevier ScienceDirect Journals
subjects AFM
Atomic force microscopy
Biocompatible Materials - chemistry
Biological and medical sciences
Biopolymers
Grafts
Guided Tissue Regeneration - instrumentation
Guided Tissue Regeneration - methods
Image processing
Medical sciences
Microgeometry
Microscopy, Atomic Force
Microscopy, Electron, Scanning
Nerve guidance channels
Nerve Regeneration
Polyurethanes
Polyurethanes - chemistry
Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)
Scanning electron microscopy
SEM
Silastic
Surface Properties
Surface roughness
Surface structure
Technology. Biomaterials. Equipments. Material. Instrumentation
title Manufacturing and microscopical characterisation of polyurethane nerve guidance channel featuring a highly smooth internal surface
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