Sex determination in platypus and echidna: autosomal location of SOX3 confirms the absence of SRY from monotremes

In eutherian ('placental') mammals, sex is determined by the presence or absence of the Y chromosome-borne gene SRY, which triggers testis determination. Marsupials also have a Y-borne SRY gene, implying that this mechanism is ancestral to therians, the SRY gene having diverged from its X-...

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Veröffentlicht in:	Chromosome research 2007-12, Vol.15 (8), p.949-959
Hauptverfasser:	Wallis, M. C, Waters, P. D, Delbridge, M. L, Kirby, P. J, Pask, A. J, Grützner, F, Rens, W, Ferguson-Smith, M. A, Graves, J. A. M
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Chromosome Painting Chromosomes DNA-Binding Proteins - genetics Echidna Echidna - genetics Genomics High Mobility Group Proteins - genetics In Situ Hybridization, Fluorescence Molecular Sequence Data Ornithorhynchus anatinus Platypus Platypus - genetics Population genetics Prototheria Sequence Homology, Amino Acid sex determination Sex Determination Processes Sex-Determining Region Y Protein - genetics Sex-Determining Region Y Protein - metabolism SOX3 SOXB1 Transcription Factors SRY Tachyglossus aculeatus Transcription Factors - genetics X Chromosome - genetics Y Chromosome - genetics
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