Preparation of casein–chitosan microspheres containing diltiazem hydrochloride by an aqueous coacervation technique

Sustained release casein–chitosan microspheres containing diltiazem hydrochloride (DTZ) were prepared with colloidal coacervation technique in a completely aqueous environment. The interaction between chitosan solution in dilute acetic acid (5% v/v) and casein solution in 0.5 M sodium hydroxide was...

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