Comparative effects of synthetic pentasaccharide, low-molecular-weight heparin, unfractionated heparin and recombinant hirudin on the generation of factor VIIa and prothrombin activation after coagulation of human plasma

We studied the effect of synthetic pentasaccharide, a low-molecular-weight heparin (enoxaparin), unfractionated heparin and recombinant hirudin on the generation of factor VIIa (FVIIa) and prothrombin activation after in-vitro clotting of human platelet-poor plasma. FVIIa was measured with a new clo...

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Veröffentlicht in:	Blood coagulation & fibrinolysis 1998-10, Vol.9 (7), p.571-580
Hauptverfasser:	Gerotziafas, G T, Bara, L, Bloch, M F, Makris, P E, Samama, M M
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Blood Coagulation Blood. Blood coagulation. Reticuloendothelial system Factor VIIa - metabolism Fibrinolytic Agents - pharmacology Heparin - pharmacology Heparin, Low-Molecular-Weight - pharmacology Hirudins - pharmacology Humans Medical sciences Pharmacology. Drug treatments Polysaccharides - chemistry Polysaccharides - pharmacology Prothrombin - metabolism Recombinant Proteins - pharmacology
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