Studies in a co-infection murine model of Plasmodium chabaudi chabaudi and Leishmania infantum: interferon-gamma and interleukin-4 mRNA expression

This work aimed to study the T helper type 1/2 (Th1/Th2) cytokine profile in a co-infection murine model of Plasmodium chabaudi chabaudi and Leishmania infantum. Expression of interferon-gamma (IFN-gamma) and interleukin-4 (IL-4) was analyzed, in spleen and liver of C57BL/6 mice, by reverse transcri...

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Veröffentlicht in:	Memórias do Instituto Oswaldo Cruz 2005-12, Vol.100 (8), p.889-892
Hauptverfasser:	Marques, Cláudia S, Rolão, Nuno, Centeno-Lima, Sónia, Lousada, Hélder, Maia, Carla, Campino, Lenea, do Rosário, Virgílio E, Silveira, Henrique
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Disease Models, Animal Female Interferon-gamma - analysis Interferon-gamma - genetics Interleukin-4 - analysis Interleukin-4 - genetics Leishmania infantum Leishmania infantum - immunology Leishmaniasis, Visceral - complications Leishmaniasis, Visceral - immunology Liver - immunology Liver - parasitology Malaria - complications Malaria - immunology Mice Mice, Inbred C57BL Parasitemia - immunology Plasmodium chabaudi - immunology Plasmodium chabaudi chabaudi Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - analysis RNA, Protozoan - analysis Spleen - immunology Spleen - parasitology Th1 Cells - immunology Th2 Cells - immunology
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