Feasibility study of lactate imaging of head and neck tumors
A proton spectroscopic imaging sequence was used to investigate the feasibility of lactate imaging in head and neck tumors. The sequence employs a two‐shot lactate editing method with inversion recovery for additional lipid suppression, and a restricted field of view to suppress motion artifacts. Va...
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| Veröffentlicht in: | NMR in biomedicine 1998-11, Vol.11 (7), p.360-369 |
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| container_title | NMR in biomedicine |
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| creator | Adalsteinsson, E. Spielman, D. M. Pauly, J. M. Terris, D. J. Sommer, G. Macovski, A. |
| description | A proton spectroscopic imaging sequence was used to investigate the feasibility of lactate imaging in head and neck tumors. The sequence employs a two‐shot lactate editing method with inversion recovery for additional lipid suppression, and a restricted field of view to suppress motion artifacts. Variations in acquisition parameters and two different receive coils were investigated on twelve patients. Elevated lactate was detected in three patients, no lactate was observed in seven patients, and two studies were inconclusive because of severe motion or inhomogeneity artifacts. Best results were obtained with an anterior/posterior neck coil at a 288 ms echo time (TE). © 1998 John Wiley & Sons, Ltd. |
| doi_str_mv | 10.1002/(SICI)1099-1492(1998110)11:7<360::AID-NBM518>3.0.CO;2-P |
| format | Article |
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M.</creatorcontrib><creatorcontrib>Pauly, J. M.</creatorcontrib><creatorcontrib>Terris, D. J.</creatorcontrib><creatorcontrib>Sommer, G.</creatorcontrib><creatorcontrib>Macovski, A.</creatorcontrib><title>Feasibility study of lactate imaging of head and neck tumors</title><title>NMR in biomedicine</title><addtitle>NMR Biomed</addtitle><description>A proton spectroscopic imaging sequence was used to investigate the feasibility of lactate imaging in head and neck tumors. The sequence employs a two‐shot lactate editing method with inversion recovery for additional lipid suppression, and a restricted field of view to suppress motion artifacts. Variations in acquisition parameters and two different receive coils were investigated on twelve patients. Elevated lactate was detected in three patients, no lactate was observed in seven patients, and two studies were inconclusive because of severe motion or inhomogeneity artifacts. Best results were obtained with an anterior/posterior neck coil at a 288 ms echo time (TE). © 1998 John Wiley & Sons, Ltd.</description><subject>Adult</subject><subject>Aged</subject><subject>Feasibility Studies</subject><subject>Female</subject><subject>Head and Neck Neoplasms - chemistry</subject><subject>Head and Neck Neoplasms - pathology</subject><subject>Head and Neck Neoplasms - surgery</subject><subject>head and neck tumors</subject><subject>Humans</subject><subject>in vivo lactate</subject><subject>lactic acid</subject><subject>Lactic Acid - analysis</subject><subject>Magnetic Resonance Spectroscopy</subject><subject>Male</subject><subject>Middle Aged</subject><subject>spectroscopic imaging</subject><subject>squamous cell carcinoma</subject><issn>0952-3480</issn><issn>1099-1492</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1998</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkF1v0zAUhi0EGmXwE5ByhbaLlOOv2C4TaGSsq7StkwoMuDlyEmcLS5sRJ2L990uUqDcg7epI5-N57YeQTxSmFIC9P1gt4sUhBWNCKgw7oMZoSuGQ0pk64hHMZseLk_Dy84Wk-iOfwjRefmDh1TMy2d08JxMwkoVcaHhJXnn_GwC04GyP7BktjRFsQo5OnfVFUpRFsw1802bboMqD0qaNbVxQrO1NsbnpW7fOZoHdZMHGpXdB066r2r8mL3JbevdmrPvk2-mXr_FZeL6cL-Lj8zAVWupQsMRkwlGuUw2pEFxKUCBsymWeOiUjLUymNUQ5tYbmwHmiJQNnIbJURwnfJ-8G7n1d_Wmdb3Bd-NSVpd24qvUYGdBKKdEtXg-LaV15X7sc7-vuD_UWKWDvFbH3ir0j7B3h6BUpRYWdV8TOKw5ekSNgvESGVx357fiENlm7bMcdRXbzn8P8b1G67T-xT6X-N3TsdOxwYBe-cQ87tq3vMFJcSby-nOOc_Thb_fq-whP-CGkPoQs</recordid><startdate>199811</startdate><enddate>199811</enddate><creator>Adalsteinsson, E.</creator><creator>Spielman, D. 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J. ; Sommer, G. ; Macovski, A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4858-42b9d4e138c80c443550704ac35fce756849d8806f1a91f033b8520ea06a186b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1998</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Feasibility Studies</topic><topic>Female</topic><topic>Head and Neck Neoplasms - chemistry</topic><topic>Head and Neck Neoplasms - pathology</topic><topic>Head and Neck Neoplasms - surgery</topic><topic>head and neck tumors</topic><topic>Humans</topic><topic>in vivo lactate</topic><topic>lactic acid</topic><topic>Lactic Acid - analysis</topic><topic>Magnetic Resonance Spectroscopy</topic><topic>Male</topic><topic>Middle Aged</topic><topic>spectroscopic imaging</topic><topic>squamous cell carcinoma</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Adalsteinsson, E.</creatorcontrib><creatorcontrib>Spielman, D. M.</creatorcontrib><creatorcontrib>Pauly, J. M.</creatorcontrib><creatorcontrib>Terris, D. J.</creatorcontrib><creatorcontrib>Sommer, G.</creatorcontrib><creatorcontrib>Macovski, A.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>NMR in biomedicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Adalsteinsson, E.</au><au>Spielman, D. M.</au><au>Pauly, J. M.</au><au>Terris, D. J.</au><au>Sommer, G.</au><au>Macovski, A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Feasibility study of lactate imaging of head and neck tumors</atitle><jtitle>NMR in biomedicine</jtitle><addtitle>NMR Biomed</addtitle><date>1998-11</date><risdate>1998</risdate><volume>11</volume><issue>7</issue><spage>360</spage><epage>369</epage><pages>360-369</pages><issn>0952-3480</issn><eissn>1099-1492</eissn><abstract>A proton spectroscopic imaging sequence was used to investigate the feasibility of lactate imaging in head and neck tumors. The sequence employs a two‐shot lactate editing method with inversion recovery for additional lipid suppression, and a restricted field of view to suppress motion artifacts. Variations in acquisition parameters and two different receive coils were investigated on twelve patients. 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| ispartof | NMR in biomedicine, 1998-11, Vol.11 (7), p.360-369 |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Adult Aged Feasibility Studies Female Head and Neck Neoplasms - chemistry Head and Neck Neoplasms - pathology Head and Neck Neoplasms - surgery head and neck tumors Humans in vivo lactate lactic acid Lactic Acid - analysis Magnetic Resonance Spectroscopy Male Middle Aged spectroscopic imaging squamous cell carcinoma |
| title | Feasibility study of lactate imaging of head and neck tumors |
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