Neuraminidase Inhibitor Susceptibility Network position statement : antiviral resistance in influenza A/H5N1 viruses

The emerging epidemic of H5N1 avian influenza virus with spillover into the human population in Asia has provoked intense concern globally about the potential of these particularly pathogenic viruses to evolve with the capacity for human-to-human transmission with a consequent pandemic. The availabi...

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Veröffentlicht in:Antiviral therapy 2005-01, Vol.10 (8), p.873-877
Hauptverfasser: HAYDEN, Frederick, KLIMOV, Alexander, ZAMBON, Maria, TASHIRO, Masato, HAY, Alan, MONTO, Arnold, MCKIMM-BRESCHKIN, Jennifer, MACKEN, Catherine, HAMPSON, Alan, WEBSTER, Robert G, AMYARD, Michele
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container_issue 8
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container_title Antiviral therapy
container_volume 10
creator HAYDEN, Frederick
KLIMOV, Alexander
ZAMBON, Maria
TASHIRO, Masato
HAY, Alan
MONTO, Arnold
MCKIMM-BRESCHKIN, Jennifer
MACKEN, Catherine
HAMPSON, Alan
WEBSTER, Robert G
AMYARD, Michele
description The emerging epidemic of H5N1 avian influenza virus with spillover into the human population in Asia has provoked intense concern globally about the potential of these particularly pathogenic viruses to evolve with the capacity for human-to-human transmission with a consequent pandemic. The availability of antiviral drugs with activity against influenza A viruses and the recognition of drug-resistant variants to these drugs prompted the following report by a select group of the global experts--members of the Neuraminidase Inhibitor Susceptibility Network--on the best use of the available drugs, both for prophylaxis and treatment. The editors of Antiviral Therapy are pleased to be able to provide this document in an expeditious manner.
doi_str_mv 10.1177/135965350501000811
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subjects Acetamides - pharmacology
Antibiotics. Antiinfectious agents. Antiparasitic agents
Antiviral agents
Biological and medical sciences
Computer Communication Networks
Drug Resistance, Viral
Enzyme Inhibitors - pharmacology
Enzyme Inhibitors - therapeutic use
Guanidines - pharmacology
Humans
Influenza A Virus, H5N1 Subtype - drug effects
Influenza, Human - drug therapy
Medical sciences
Neuraminidase - antagonists & inhibitors
Oseltamivir
Pharmacology. Drug treatments
Pyrans - pharmacology
Sialic Acids - pharmacology
Viral Matrix Proteins - antagonists & inhibitors
Zanamivir
title Neuraminidase Inhibitor Susceptibility Network position statement : antiviral resistance in influenza A/H5N1 viruses
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