Docosahexaenoic acid decreases phospholipase A2 activity in the neurites/nerve growth cones of PC12 cells

Docosahexaenoic acid (DHA) accumulates in nerve growth cones (NGC) during perinatal development and it is neuroprotective in ischemia. Because the phospholipases A2 (PLA2) are present in NGC and these enzymes function in both ischemia and long‐term potentiation, the relationship between DHA and PLA2...

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Veröffentlicht in:	Journal of neuroscience research 1998-12, Vol.54 (6), p.805-813
1. Verfasser:	Martin, Rex E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Differentiation Cell Line, Transformed docosahexaenoic acid Docosahexaenoic Acids - metabolism Docosahexaenoic Acids - pharmacology Ethanolamines fatty acid Growth Cones - drug effects Growth Cones - enzymology Neurites - drug effects Neurites - enzymology neuronal development/differentiation nutrition omega-3 (n-3) PC12 Cells phospholipase A Phospholipases A - drug effects Phospholipases A - metabolism Phospholipases A2 Rats
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