Treatment of a septic shock due to multiresistant Acinetobacter baumannii with tigecycline in combination
We report a case of pulmonary and bloodstream infection due to multiresistant Acinetobacter baumannii six days after a severe trauma. Clinical condition transiently improved following antimicrobial treatment with ticarcillin-clavulanate and rifampicin. However, a septic shock developed on the fourth...
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Veröffentlicht in: | Annales françaises d'anesthésie et de réanimation 2007-12, Vol.26 (12), p.1056-1058 |
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description | We report a case of pulmonary and bloodstream infection due to multiresistant Acinetobacter baumannii six days after a severe trauma. Clinical condition transiently improved following antimicrobial treatment with ticarcillin-clavulanate and rifampicin. However, a septic shock developed on the fourth day due to the emergence of a strain only sensible to cotrimoxazole, colistin and tigecycline. Cure was achieved after a two week treatment with piperacillin-tazobactam, cotrimoxazole and tigecycline. This case shows that combined antimicrobial therapy including tigecycline can be relevant in some severe pulmonary infections due to multiresistant A. baumannii. |
doi_str_mv | 10.1016/j.annfar.2007.08.015 |
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Clinical condition transiently improved following antimicrobial treatment with ticarcillin-clavulanate and rifampicin. However, a septic shock developed on the fourth day due to the emergence of a strain only sensible to cotrimoxazole, colistin and tigecycline. Cure was achieved after a two week treatment with piperacillin-tazobactam, cotrimoxazole and tigecycline. This case shows that combined antimicrobial therapy including tigecycline can be relevant in some severe pulmonary infections due to multiresistant A. baumannii.</description><identifier>EISSN: 1769-6623</identifier><identifier>DOI: 10.1016/j.annfar.2007.08.015</identifier><identifier>PMID: 17961967</identifier><language>fre</language><publisher>France</publisher><subject><![CDATA[Acinetobacter baumannii ; Acinetobacter Infections - complications ; Adolescent ; Anti-Bacterial Agents - administration & dosage ; Anti-Infective Agents - administration & dosage ; Drug Resistance, Multiple, Bacterial ; Drug Therapy, Combination ; Female ; Humans ; Minocycline - administration & dosage ; Minocycline - analogs & derivatives ; Penicillanic Acid - administration & dosage ; Penicillanic Acid - analogs & derivatives ; Piperacillin - administration & dosage ; Shock, Septic - drug therapy ; Shock, Septic - microbiology ; Trimethoprim, Sulfamethoxazole Drug Combination - administration & dosage]]></subject><ispartof>Annales françaises d'anesthésie et de réanimation, 2007-12, Vol.26 (12), p.1056-1058</ispartof><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,778,782,27911,27912</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17961967$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Leclerc, T</creatorcontrib><creatorcontrib>Perez, J-P</creatorcontrib><creatorcontrib>Debien, B</creatorcontrib><creatorcontrib>Clapson, P</creatorcontrib><creatorcontrib>Lenoir, B</creatorcontrib><title>Treatment of a septic shock due to multiresistant Acinetobacter baumannii with tigecycline in combination</title><title>Annales françaises d'anesthésie et de réanimation</title><addtitle>Ann Fr Anesth Reanim</addtitle><description>We report a case of pulmonary and bloodstream infection due to multiresistant Acinetobacter baumannii six days after a severe trauma. 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subjects | Acinetobacter baumannii Acinetobacter Infections - complications Adolescent Anti-Bacterial Agents - administration & dosage Anti-Infective Agents - administration & dosage Drug Resistance, Multiple, Bacterial Drug Therapy, Combination Female Humans Minocycline - administration & dosage Minocycline - analogs & derivatives Penicillanic Acid - administration & dosage Penicillanic Acid - analogs & derivatives Piperacillin - administration & dosage Shock, Septic - drug therapy Shock, Septic - microbiology Trimethoprim, Sulfamethoxazole Drug Combination - administration & dosage |
title | Treatment of a septic shock due to multiresistant Acinetobacter baumannii with tigecycline in combination |
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