Treatment of a septic shock due to multiresistant Acinetobacter baumannii with tigecycline in combination

We report a case of pulmonary and bloodstream infection due to multiresistant Acinetobacter baumannii six days after a severe trauma. Clinical condition transiently improved following antimicrobial treatment with ticarcillin-clavulanate and rifampicin. However, a septic shock developed on the fourth...

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Veröffentlicht in:Annales françaises d'anesthésie et de réanimation 2007-12, Vol.26 (12), p.1056-1058
Hauptverfasser: Leclerc, T, Perez, J-P, Debien, B, Clapson, P, Lenoir, B
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container_title Annales françaises d'anesthésie et de réanimation
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creator Leclerc, T
Perez, J-P
Debien, B
Clapson, P
Lenoir, B
description We report a case of pulmonary and bloodstream infection due to multiresistant Acinetobacter baumannii six days after a severe trauma. Clinical condition transiently improved following antimicrobial treatment with ticarcillin-clavulanate and rifampicin. However, a septic shock developed on the fourth day due to the emergence of a strain only sensible to cotrimoxazole, colistin and tigecycline. Cure was achieved after a two week treatment with piperacillin-tazobactam, cotrimoxazole and tigecycline. This case shows that combined antimicrobial therapy including tigecycline can be relevant in some severe pulmonary infections due to multiresistant A. baumannii.
doi_str_mv 10.1016/j.annfar.2007.08.015
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source MEDLINE; ScienceDirect Journals (5 years ago - present)
subjects Acinetobacter baumannii
Acinetobacter Infections - complications
Adolescent
Anti-Bacterial Agents - administration & dosage
Anti-Infective Agents - administration & dosage
Drug Resistance, Multiple, Bacterial
Drug Therapy, Combination
Female
Humans
Minocycline - administration & dosage
Minocycline - analogs & derivatives
Penicillanic Acid - administration & dosage
Penicillanic Acid - analogs & derivatives
Piperacillin - administration & dosage
Shock, Septic - drug therapy
Shock, Septic - microbiology
Trimethoprim, Sulfamethoxazole Drug Combination - administration & dosage
title Treatment of a septic shock due to multiresistant Acinetobacter baumannii with tigecycline in combination
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