Enhanced Chondrogenesis and Wnt Signaling in PTH‐Treated Fractures

Studies have shown that systemic PTH treatment enhanced the rate of bone repair in rodent models. However, the mechanisms through which PTH affects bone repair have not been elucidated. In these studies we show that PTH primarily enhanced the earliest stages of endochondral bone repair by increasing...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of bone and mineral research 2007-12, Vol.22 (12), p.1903-1912
Hauptverfasser:	Kakar, Sanjeev, Einhorn, Thomas A, Vora, Siddharth, Miara, Lincoln J, Hon, Gregory, Wigner, Nathan A, Toben, Daniel, Jacobsen, Kimberly A, Al‐Sebaei, Maisa O, Song, Michael, Trackman, Philip C, Morgan, Elise F, Gerstenfeld, Louis C, Barnes, George L
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Bone Density Conservation Agents - pharmacology Cell Differentiation - drug effects Chondrocytes - metabolism Chondrocytes - pathology chondrogenesis Chondrogenesis - drug effects Disease Models, Animal endochondral bone repair Femoral Fractures - drug therapy Femoral Fractures - metabolism Femoral Fractures - pathology fracture Fracture Healing - drug effects Fundamental and applied biological sciences. Psychology Male Mice osteogenesis PTH Signal Transduction - drug effects Skeleton and joints Teriparatide - pharmacology Vertebrates: osteoarticular system, musculoskeletal system Wnt Proteins - metabolism Wnts β‐catenin
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!