Dihydrotrichodimerol and Tetrahydrotrichodimerol, Two New Bisorbicillinoids, from a Marine-derived Penicillium terrestre
Two new bisorbicillinoids possessing an open-ended cage structure, dihydrotrichodimerol ( 1 ) and tetrahydrotrichodimerol ( 2 ), were isolated from a marine-derived Penicillium terrestre . Their structures were established by spectroscopic methods. Their cytotoxic activities against P388 and A-549 c...
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| Veröffentlicht in: | Journal of antibiotics 2005-10, Vol.58 (10), p.621-624 |
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| container_issue | 10 |
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| container_title | Journal of antibiotics |
| container_volume | 58 |
| creator | Liu, Weizhong Gu, Qianqun Zhu, Weiming Cui, Chengbin Fan, Guotao |
| description | Two new bisorbicillinoids possessing an open-ended cage structure, dihydrotrichodimerol (
1
) and tetrahydrotrichodimerol (
2
), were isolated from a marine-derived
Penicillium terrestre
. Their structures were established by spectroscopic methods. Their cytotoxic activities against P388 and A-549 cell lines were preliminarily evaluated by the MTT method. |
| doi_str_mv | 10.1038/ja.2005.85 |
| format | Article |
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1
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Penicillium terrestre
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| fulltext | fulltext |
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| ispartof | Journal of antibiotics, 2005-10, Vol.58 (10), p.621-624 |
| issn | 0021-8820 1881-1469 |
| language | eng |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Bacteriology Biomedical and Life Sciences Bioorganic Chemistry Bridged-Ring Compounds - chemistry Bridged-Ring Compounds - isolation & purification Bridged-Ring Compounds - pharmacology Cell Line Life Sciences Marine Marine Biology Medicinal Chemistry Microbiology Organic Chemistry original-article Penicillium Penicillium - chemistry Penicillium terrestre |
| title | Dihydrotrichodimerol and Tetrahydrotrichodimerol, Two New Bisorbicillinoids, from a Marine-derived Penicillium terrestre |
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