Circulating levels of tumor necrosis factor receptors are highly predictive of mortality in patients with rheumatoid arthritis

Objective To investigate whether circulating levels of soluble tumor necrosis factor receptors (sTNFR) are predictive of mortality in rheumatoid arthritis (RA). Methods Levels of sTNFRI and sTNFRII at study entry were quantified using enzyme‐linked immunosorbent assays in sera from 401 white patient...

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Veröffentlicht in:	Arthritis and rheumatism 2007-12, Vol.56 (12), p.3940-3948
Hauptverfasser:	Mattey, Derek L., Glossop, John R., Nixon, Nicola B., Dawes, Peter T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Arthritis, Rheumatoid - complications Arthritis, Rheumatoid - mortality Biological and medical sciences Cardiovascular Diseases - complications Cardiovascular Diseases - mortality Diseases of the osteoarticular system Female Follow-Up Studies Humans Inflammatory joint diseases Kaplan-Meier Estimate Lung Diseases - complications Lung Diseases - mortality Male Medical sciences Middle Aged Multivariate Analysis Predictive Value of Tests Proportional Hazards Models Receptors, Tumor Necrosis Factor, Type I - blood Receptors, Tumor Necrosis Factor, Type II - blood ROC Curve Tobacco, tobacco smoking Toxicology
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