Intra-Abdominal Use of Taurolidine or Heparin as Alternative Products to an Antiadhesive Barrier (Seprafilm®) in Adhesion Prevention: An Experimental Study on Mice
PURPOSE: METHODS: RESULTS:Five (1 in Group S and 4 in Group H) animals died before they were killed. The deaths were related to intra-abdominal bleeding, and mortality rate was significantly higher in Group H than those in other groups (P < 0.05 for each comparison). The severity of adhesions was...
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| Veröffentlicht in: | Diseases of the colon & rectum 2007-12, Vol.50 (12), p.2209-2214 |
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| container_issue | 12 |
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| container_title | Diseases of the colon & rectum |
| container_volume | 50 |
| creator | Bahadir, Isamettin Oncel, Mustafa Kement, Metin Sahip, Yusuf |
| description | PURPOSE:
METHODS:
RESULTS:Five (1 in Group S and 4 in Group H) animals died before they were killed. The deaths were related to intra-abdominal bleeding, and mortality rate was significantly higher in Group H than those in other groups (P < 0.05 for each comparison). The severity of adhesions was significantly less in the study groups than Group C, and in Group H than Groups T and S (P < 0.05 for each comparison). In addition, adhesions located cecum over itself were significantly less in the study groups than the control group, and those between small bowel and cecum were significantly lower in Groups T and S than the control group (P < 0.05 for each comparison).
CONCLUSIONS: |
| doi_str_mv | 10.1007/s10350-007-9074-6 |
| format | Article |
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METHODS:
RESULTS:Five (1 in Group S and 4 in Group H) animals died before they were killed. The deaths were related to intra-abdominal bleeding, and mortality rate was significantly higher in Group H than those in other groups (P < 0.05 for each comparison). The severity of adhesions was significantly less in the study groups than Group C, and in Group H than Groups T and S (P < 0.05 for each comparison). In addition, adhesions located cecum over itself were significantly less in the study groups than the control group, and those between small bowel and cecum were significantly lower in Groups T and S than the control group (P < 0.05 for each comparison).
CONCLUSIONS:</description><identifier>ISSN: 0012-3706</identifier><identifier>EISSN: 1530-0358</identifier><identifier>DOI: 10.1007/s10350-007-9074-6</identifier><identifier>PMID: 17902020</identifier><identifier>CODEN: DICRAG</identifier><language>eng</language><publisher>Secaucus, NJ: The ASCRS</publisher><subject><![CDATA[Abdominal Cavity ; Animals ; Antineoplastic Agents - administration & dosage ; Biological and medical sciences ; Digestive System Surgical Procedures - adverse effects ; Disease Models, Animal ; Fibrinolytic Agents - administration & dosage ; Heparin - administration & dosage ; Hyaluronic Acid - administration & dosage ; Male ; Medical sciences ; Membranes, Artificial ; Mice ; Mice, Inbred BALB C ; Postoperative Complications - prevention & control ; Stomach, duodenum, intestine, rectum, anus ; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases ; Surgery of the digestive system ; Taurine - administration & dosage ; Taurine - analogs & derivatives ; Thiadiazines - administration & dosage ; Tissue Adhesions - prevention & control ; Treatment Outcome]]></subject><ispartof>Diseases of the colon & rectum, 2007-12, Vol.50 (12), p.2209-2214</ispartof><rights>The ASCRS 2007</rights><rights>2008 INIST-CNRS</rights><rights>American Society of Colon and Rectal Surgeons 2007</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4675-364e6f5cf46999a34aa559ed8c4526c6ecf6e6576cd5b36ec44734406e1a1be13</citedby><cites>FETCH-LOGICAL-c4675-364e6f5cf46999a34aa559ed8c4526c6ecf6e6576cd5b36ec44734406e1a1be13</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=19964189$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17902020$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bahadir, Isamettin</creatorcontrib><creatorcontrib>Oncel, Mustafa</creatorcontrib><creatorcontrib>Kement, Metin</creatorcontrib><creatorcontrib>Sahip, Yusuf</creatorcontrib><title>Intra-Abdominal Use of Taurolidine or Heparin as Alternative Products to an Antiadhesive Barrier (Seprafilm®) in Adhesion Prevention: An Experimental Study on Mice</title><title>Diseases of the colon & rectum</title><addtitle>Dis Colon Rectum</addtitle><description>PURPOSE:
METHODS:
RESULTS:Five (1 in Group S and 4 in Group H) animals died before they were killed. The deaths were related to intra-abdominal bleeding, and mortality rate was significantly higher in Group H than those in other groups (P < 0.05 for each comparison). The severity of adhesions was significantly less in the study groups than Group C, and in Group H than Groups T and S (P < 0.05 for each comparison). In addition, adhesions located cecum over itself were significantly less in the study groups than the control group, and those between small bowel and cecum were significantly lower in Groups T and S than the control group (P < 0.05 for each comparison).
CONCLUSIONS:</description><subject>Abdominal Cavity</subject><subject>Animals</subject><subject>Antineoplastic Agents - administration & dosage</subject><subject>Biological and medical sciences</subject><subject>Digestive System Surgical Procedures - adverse effects</subject><subject>Disease Models, Animal</subject><subject>Fibrinolytic Agents - administration & dosage</subject><subject>Heparin - administration & dosage</subject><subject>Hyaluronic Acid - administration & dosage</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Membranes, Artificial</subject><subject>Mice</subject><subject>Mice, Inbred BALB C</subject><subject>Postoperative Complications - prevention & control</subject><subject>Stomach, duodenum, intestine, rectum, anus</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</subject><subject>Surgery of the digestive system</subject><subject>Taurine - administration & dosage</subject><subject>Taurine - analogs & derivatives</subject><subject>Thiadiazines - administration & dosage</subject><subject>Tissue Adhesions - prevention & control</subject><subject>Treatment Outcome</subject><issn>0012-3706</issn><issn>1530-0358</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdks9u1DAQxiMEokvhAbggCwlUDgE7_pMNt1AVWqkIpLbnaNaZaF289mInLX0fzn0InowJu1IlLvaM_ftmbH8uipeCvxec1x-y4FLzksKy4bUqzaNiIbSkFamXj4sF56IqZc3NQfEs52tKecXrp8WBqBuKKr4ofp-FMUHZrvq4cQE8u8rI4sAuYUrRu94FShM7xS0kFxhk1voRU4DR3SD7nmI_2TGzMTIIrA2jg36Ned77BCk5TOzoArcJBuc3f-7fMarR_iNiIDXeIEli-EhSdvJri8ltaIWOcTFO_R0j6Kuz-Lx4MoDP-GI_HxZXn08uj0_L829fzo7b89IqU-tSGoVm0HZQpmkakApA6wb7pVW6MtagHQwaXRvb65WkVKlaKsUNChArFPKweLuru03x54R57DYuW_QeAsYpd6bhRiz5DL7-D7yOEz2Kz10lFNc0VASJHWRTzDnh0G3pepDuOsG72b9u5183h7N_nSHNq33habXB_kGxN4yAN3sAsgU_JAjW5QeuaYwSy4Y4teNu4-xX_uGnW0zdGsGPa-rIuVRalhX11vRL5k_EKy3_AgPSs8Y</recordid><startdate>200712</startdate><enddate>200712</enddate><creator>Bahadir, Isamettin</creator><creator>Oncel, Mustafa</creator><creator>Kement, Metin</creator><creator>Sahip, Yusuf</creator><general>The ASCRS</general><general>Springer</general><general>Lippincott Williams & Wilkins Ovid Technologies</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>7X8</scope></search><sort><creationdate>200712</creationdate><title>Intra-Abdominal Use of Taurolidine or Heparin as Alternative Products to an Antiadhesive Barrier (Seprafilm®) in Adhesion Prevention: An Experimental Study on Mice</title><author>Bahadir, Isamettin ; Oncel, Mustafa ; Kement, Metin ; Sahip, Yusuf</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4675-364e6f5cf46999a34aa559ed8c4526c6ecf6e6576cd5b36ec44734406e1a1be13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Abdominal Cavity</topic><topic>Animals</topic><topic>Antineoplastic Agents - administration & dosage</topic><topic>Biological and medical sciences</topic><topic>Digestive System Surgical Procedures - adverse effects</topic><topic>Disease Models, Animal</topic><topic>Fibrinolytic Agents - administration & dosage</topic><topic>Heparin - administration & dosage</topic><topic>Hyaluronic Acid - administration & dosage</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Membranes, Artificial</topic><topic>Mice</topic><topic>Mice, Inbred BALB C</topic><topic>Postoperative Complications - prevention & control</topic><topic>Stomach, duodenum, intestine, rectum, anus</topic><topic>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</topic><topic>Surgery of the digestive system</topic><topic>Taurine - administration & dosage</topic><topic>Taurine - analogs & derivatives</topic><topic>Thiadiazines - administration & dosage</topic><topic>Tissue Adhesions - prevention & control</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bahadir, Isamettin</creatorcontrib><creatorcontrib>Oncel, Mustafa</creatorcontrib><creatorcontrib>Kement, Metin</creatorcontrib><creatorcontrib>Sahip, Yusuf</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>Diseases of the colon & rectum</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bahadir, Isamettin</au><au>Oncel, Mustafa</au><au>Kement, Metin</au><au>Sahip, Yusuf</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Intra-Abdominal Use of Taurolidine or Heparin as Alternative Products to an Antiadhesive Barrier (Seprafilm®) in Adhesion Prevention: An Experimental Study on Mice</atitle><jtitle>Diseases of the colon & rectum</jtitle><addtitle>Dis Colon Rectum</addtitle><date>2007-12</date><risdate>2007</risdate><volume>50</volume><issue>12</issue><spage>2209</spage><epage>2214</epage><pages>2209-2214</pages><issn>0012-3706</issn><eissn>1530-0358</eissn><coden>DICRAG</coden><abstract>PURPOSE:
METHODS:
RESULTS:Five (1 in Group S and 4 in Group H) animals died before they were killed. The deaths were related to intra-abdominal bleeding, and mortality rate was significantly higher in Group H than those in other groups (P < 0.05 for each comparison). The severity of adhesions was significantly less in the study groups than Group C, and in Group H than Groups T and S (P < 0.05 for each comparison). In addition, adhesions located cecum over itself were significantly less in the study groups than the control group, and those between small bowel and cecum were significantly lower in Groups T and S than the control group (P < 0.05 for each comparison).
CONCLUSIONS:</abstract><cop>Secaucus, NJ</cop><pub>The ASCRS</pub><pmid>17902020</pmid><doi>10.1007/s10350-007-9074-6</doi><tpages>6</tpages></addata></record> |
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| source | MEDLINE; SpringerLink Journals - AutoHoldings; Journals@Ovid Complete |
| subjects | Abdominal Cavity Animals Antineoplastic Agents - administration & dosage Biological and medical sciences Digestive System Surgical Procedures - adverse effects Disease Models, Animal Fibrinolytic Agents - administration & dosage Heparin - administration & dosage Hyaluronic Acid - administration & dosage Male Medical sciences Membranes, Artificial Mice Mice, Inbred BALB C Postoperative Complications - prevention & control Stomach, duodenum, intestine, rectum, anus Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the digestive system Taurine - administration & dosage Taurine - analogs & derivatives Thiadiazines - administration & dosage Tissue Adhesions - prevention & control Treatment Outcome |
| title | Intra-Abdominal Use of Taurolidine or Heparin as Alternative Products to an Antiadhesive Barrier (Seprafilm®) in Adhesion Prevention: An Experimental Study on Mice |
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