N-Acetyltransferase Polymorphism Among Northern Sudanese

Interindividual and interethnic differences in allele frequencies of N-acetyltransferase (NAT2) single nucleotide polymorphisms (SNPs) are responsible for phenotypic variability of adverse drug reactions and susceptibility to cancer. We genotyped the seven NAT2 common SNPs in 127 randomly selected u...

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Veröffentlicht in:	Human biology 2007-08, Vol.79 (4), p.445-452
Hauptverfasser:	Al-Yahyaee, Said, Gaffar, Uzma, Al-Ameri, Maryam M., Qureshi, Mansoor, Zadjali, Fahad, Ali, Baderldin H., Bayoumi, Riad
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylation Adolescent Adult AFRICA ALLELE HAPLOTYPE Alleles Allelomorphism Amino acids Arylamine N-Acetyltransferase - genetics BIOINFORMATICS TOOLS Biological anthropology CANCER Child Computer analysis Computers, Molecular Demographic aspects Demographic research Disease susceptibility DNA Drug therapy DRUG TOXICITY DRUG-METABOLIZING ENZYMES Drugs Enzymes Ethnic groups Female Gene frequency Genetic aspects Genetics Genotype Genotype & phenotype Genotypes Geography Haplotypes Health aspects Human biology Humans Identification and classification Inheritance Kinship Male Middle Aged Minority & ethnic groups N-ACETYLTRANSFERASE (NAT2) Pharmacogenetics Phenotype Phenotypes Polymerase chain reaction Polymorphism, Genetic Polymorphism, Restriction Fragment Length Properties s Single nucleotide polymorphisms Sudan SUDANESE
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