Clinical/Pathologic Correlations in 553 Patients With Primary Centrilobular Findings on High-Resolution CT Scan of the Thorax
Clinical/pathologic correlations in patients with high-resolution CT (HRCT) scan findings presenting with two patterns of centrilobular opacity remain unclear. Chest HRCT scans in 553 patients with predominant centrilobular opacities or preferential centrilobular disease were retrospectively evaluat...
Gespeichert in:
| Veröffentlicht in: | Chest 2007-12, Vol.132 (6), p.1939-1948 |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1948 |
|---|---|
| container_issue | 6 |
| container_start_page | 1939 |
| container_title | Chest |
| container_volume | 132 |
| creator | Okada, Fumito Ando, Yumiko Yoshitake, Sachie Ono, Asami Tanoue, Shuichi Matsumoto, Shunro Wakisaka, Masaki Maeda, Toru Mori, Hiromu |
| description | Clinical/pathologic correlations in patients with high-resolution CT (HRCT) scan findings presenting with two patterns of centrilobular opacity remain unclear.
Chest HRCT scans in 553 patients with predominant centrilobular opacities or preferential centrilobular disease were retrospectively evaluated. In 141 patients who underwent biopsy, CT scan images were compared with actual specimens.
Centrilobular nodules with a tree-in-bud appearance and bronchial wall thickening were observed in most patients who were carriers of human T-lymphotropic virus type 1 (88 patients and 57 of 99 patients, respectively), Mycoplasma pneumoniae pneumonia (44 patients and 45 of 52 patients, respectively), Mycobacterium tuberculosis (38 patients and 37 of 52 patients, respectively), Mycobacterium avium-intracellulare complex (22 patients and 27 of 37 patients, respectively), Mycobacterium kansasii (27 patients and 19 of 33 patients, respectively), allergic bronchopulmonary aspergillosis (6 patients and 7 of 9 patients, respectively), diffuse panbronchiolitis (12 patients and 10 of 12 patients, respectively), and diffuse aspiration bronchiolitis (12 patients and 12 of 13 patients, respectively). On the other hand, ill-defined centrilobular nodules of ground-glass attenuation were frequently seen in patients with subacute hypersensitivity pneumonitis (all 15 patients), metastatic calcification (all 4 patients), Churg-Strauss syndrome (4 of 12 patients), microscopic polyangiitis (27 of 48 patients), systemic lupus erythematosus (7 of 8 patients), and respiratory bronchiolitis-associated interstitial lung disease (all 8 patients). Pathologically, the tree-in-bud appearance correlated well with the plugging of small airways with mucous, pus, or fluid; dilated bronchioles; and bronchiolar wall thickening. Ill-defined centrilobular nodules represented peribronchiolar inflammation or the deposition of hemorrhagic materials.
Knowledge of the two centrilobular patterns is of proven worth for generating differential diagnoses and is of particular value in suggesting a likely infectious etiology in cases with tree-in-bud appearance. |
| doi_str_mv | 10.1378/chest.07-0482 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_69058537</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0012369215524707</els_id><sourcerecordid>69058537</sourcerecordid><originalsourceid>FETCH-LOGICAL-c410t-7eab67c61e94d139b9530e314dc309b255c694d6b8abfe55af17f93effead5013</originalsourceid><addsrcrecordid>eNp1kU1v3CAQhlHVqNmmOfZacWlvTsAYY46VlTSVIjVqt8oRYTysiVhIwe7Hof-9bL1STjkhmOcdhgeE3lJyQZnoLs0Eeb4goiJNV79AGyoZrRhv2Eu0IYTWFWtlfYpe5_xAyp7K9hU6pR0Rsq7FBv3tvQvOaH95p-cp-rhzBvcxJfB6djFk7ALmnOFSdhDmjO_dPOG75PY6_cF9OUrOx2HxOuFrF0YXdhnHgG_cbqq-Qo5-OfTB_RZ_MzrgaPE8Ad5OMenfb9CJ1T7D-XE9Q9-vr7b9TXX75dPn_uNtZRpK5kqAHlphWgqyGSmTg-SMAKPNaBiRQ825aUulHTo9WOBcWyqsZGAt6JETys7Qh7XvY4o_liJM7V024L0OEJesWkl4x5koYLWCJsWcE1j1uL5UUaIOvtV_34oIdfBd-HfHxsuwh_GJPgouwPsjoHOxbJMOxuUnTkoqKTtMSFZuKt5-uQQq77X3pS1br3yISwraU1artsSYLBGxRqCY--kgqWzKFxkYS9zMaozuman_AXcKrs0</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>69058537</pqid></control><display><type>article</type><title>Clinical/Pathologic Correlations in 553 Patients With Primary Centrilobular Findings on High-Resolution CT Scan of the Thorax</title><source>MEDLINE</source><source>Alma/SFX Local Collection</source><creator>Okada, Fumito ; Ando, Yumiko ; Yoshitake, Sachie ; Ono, Asami ; Tanoue, Shuichi ; Matsumoto, Shunro ; Wakisaka, Masaki ; Maeda, Toru ; Mori, Hiromu</creator><creatorcontrib>Okada, Fumito ; Ando, Yumiko ; Yoshitake, Sachie ; Ono, Asami ; Tanoue, Shuichi ; Matsumoto, Shunro ; Wakisaka, Masaki ; Maeda, Toru ; Mori, Hiromu</creatorcontrib><description>Clinical/pathologic correlations in patients with high-resolution CT (HRCT) scan findings presenting with two patterns of centrilobular opacity remain unclear.
Chest HRCT scans in 553 patients with predominant centrilobular opacities or preferential centrilobular disease were retrospectively evaluated. In 141 patients who underwent biopsy, CT scan images were compared with actual specimens.
Centrilobular nodules with a tree-in-bud appearance and bronchial wall thickening were observed in most patients who were carriers of human T-lymphotropic virus type 1 (88 patients and 57 of 99 patients, respectively), Mycoplasma pneumoniae pneumonia (44 patients and 45 of 52 patients, respectively), Mycobacterium tuberculosis (38 patients and 37 of 52 patients, respectively), Mycobacterium avium-intracellulare complex (22 patients and 27 of 37 patients, respectively), Mycobacterium kansasii (27 patients and 19 of 33 patients, respectively), allergic bronchopulmonary aspergillosis (6 patients and 7 of 9 patients, respectively), diffuse panbronchiolitis (12 patients and 10 of 12 patients, respectively), and diffuse aspiration bronchiolitis (12 patients and 12 of 13 patients, respectively). On the other hand, ill-defined centrilobular nodules of ground-glass attenuation were frequently seen in patients with subacute hypersensitivity pneumonitis (all 15 patients), metastatic calcification (all 4 patients), Churg-Strauss syndrome (4 of 12 patients), microscopic polyangiitis (27 of 48 patients), systemic lupus erythematosus (7 of 8 patients), and respiratory bronchiolitis-associated interstitial lung disease (all 8 patients). Pathologically, the tree-in-bud appearance correlated well with the plugging of small airways with mucous, pus, or fluid; dilated bronchioles; and bronchiolar wall thickening. Ill-defined centrilobular nodules represented peribronchiolar inflammation or the deposition of hemorrhagic materials.
Knowledge of the two centrilobular patterns is of proven worth for generating differential diagnoses and is of particular value in suggesting a likely infectious etiology in cases with tree-in-bud appearance.</description><identifier>ISSN: 0012-3692</identifier><identifier>EISSN: 1931-3543</identifier><identifier>DOI: 10.1378/chest.07-0482</identifier><identifier>PMID: 18079227</identifier><identifier>CODEN: CHETBF</identifier><language>eng</language><publisher>Northbrook, IL: Elsevier Inc</publisher><subject>Adolescent ; Adult ; Aged ; Aged, 80 and over ; airway infection ; Biological and medical sciences ; Biopsy ; bronchiolitis ; Cardiology. Vascular system ; Chronic obstructive pulmonary disease, asthma ; CT scan ; Diagnosis, Differential ; Female ; Humans ; Lung Diseases - diagnostic imaging ; Lung Diseases - microbiology ; Male ; Medical sciences ; Middle Aged ; Pneumology ; Radiography, Thoracic ; Retrospective Studies ; Tomography, X-Ray Computed</subject><ispartof>Chest, 2007-12, Vol.132 (6), p.1939-1948</ispartof><rights>2007 The American College of Chest Physicians</rights><rights>2008 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c410t-7eab67c61e94d139b9530e314dc309b255c694d6b8abfe55af17f93effead5013</citedby><cites>FETCH-LOGICAL-c410t-7eab67c61e94d139b9530e314dc309b255c694d6b8abfe55af17f93effead5013</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=19919131$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18079227$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Okada, Fumito</creatorcontrib><creatorcontrib>Ando, Yumiko</creatorcontrib><creatorcontrib>Yoshitake, Sachie</creatorcontrib><creatorcontrib>Ono, Asami</creatorcontrib><creatorcontrib>Tanoue, Shuichi</creatorcontrib><creatorcontrib>Matsumoto, Shunro</creatorcontrib><creatorcontrib>Wakisaka, Masaki</creatorcontrib><creatorcontrib>Maeda, Toru</creatorcontrib><creatorcontrib>Mori, Hiromu</creatorcontrib><title>Clinical/Pathologic Correlations in 553 Patients With Primary Centrilobular Findings on High-Resolution CT Scan of the Thorax</title><title>Chest</title><addtitle>Chest</addtitle><description>Clinical/pathologic correlations in patients with high-resolution CT (HRCT) scan findings presenting with two patterns of centrilobular opacity remain unclear.
Chest HRCT scans in 553 patients with predominant centrilobular opacities or preferential centrilobular disease were retrospectively evaluated. In 141 patients who underwent biopsy, CT scan images were compared with actual specimens.
Centrilobular nodules with a tree-in-bud appearance and bronchial wall thickening were observed in most patients who were carriers of human T-lymphotropic virus type 1 (88 patients and 57 of 99 patients, respectively), Mycoplasma pneumoniae pneumonia (44 patients and 45 of 52 patients, respectively), Mycobacterium tuberculosis (38 patients and 37 of 52 patients, respectively), Mycobacterium avium-intracellulare complex (22 patients and 27 of 37 patients, respectively), Mycobacterium kansasii (27 patients and 19 of 33 patients, respectively), allergic bronchopulmonary aspergillosis (6 patients and 7 of 9 patients, respectively), diffuse panbronchiolitis (12 patients and 10 of 12 patients, respectively), and diffuse aspiration bronchiolitis (12 patients and 12 of 13 patients, respectively). On the other hand, ill-defined centrilobular nodules of ground-glass attenuation were frequently seen in patients with subacute hypersensitivity pneumonitis (all 15 patients), metastatic calcification (all 4 patients), Churg-Strauss syndrome (4 of 12 patients), microscopic polyangiitis (27 of 48 patients), systemic lupus erythematosus (7 of 8 patients), and respiratory bronchiolitis-associated interstitial lung disease (all 8 patients). Pathologically, the tree-in-bud appearance correlated well with the plugging of small airways with mucous, pus, or fluid; dilated bronchioles; and bronchiolar wall thickening. Ill-defined centrilobular nodules represented peribronchiolar inflammation or the deposition of hemorrhagic materials.
Knowledge of the two centrilobular patterns is of proven worth for generating differential diagnoses and is of particular value in suggesting a likely infectious etiology in cases with tree-in-bud appearance.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>airway infection</subject><subject>Biological and medical sciences</subject><subject>Biopsy</subject><subject>bronchiolitis</subject><subject>Cardiology. Vascular system</subject><subject>Chronic obstructive pulmonary disease, asthma</subject><subject>CT scan</subject><subject>Diagnosis, Differential</subject><subject>Female</subject><subject>Humans</subject><subject>Lung Diseases - diagnostic imaging</subject><subject>Lung Diseases - microbiology</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Pneumology</subject><subject>Radiography, Thoracic</subject><subject>Retrospective Studies</subject><subject>Tomography, X-Ray Computed</subject><issn>0012-3692</issn><issn>1931-3543</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kU1v3CAQhlHVqNmmOfZacWlvTsAYY46VlTSVIjVqt8oRYTysiVhIwe7Hof-9bL1STjkhmOcdhgeE3lJyQZnoLs0Eeb4goiJNV79AGyoZrRhv2Eu0IYTWFWtlfYpe5_xAyp7K9hU6pR0Rsq7FBv3tvQvOaH95p-cp-rhzBvcxJfB6djFk7ALmnOFSdhDmjO_dPOG75PY6_cF9OUrOx2HxOuFrF0YXdhnHgG_cbqq-Qo5-OfTB_RZ_MzrgaPE8Ad5OMenfb9CJ1T7D-XE9Q9-vr7b9TXX75dPn_uNtZRpK5kqAHlphWgqyGSmTg-SMAKPNaBiRQ825aUulHTo9WOBcWyqsZGAt6JETys7Qh7XvY4o_liJM7V024L0OEJesWkl4x5koYLWCJsWcE1j1uL5UUaIOvtV_34oIdfBd-HfHxsuwh_GJPgouwPsjoHOxbJMOxuUnTkoqKTtMSFZuKt5-uQQq77X3pS1br3yISwraU1artsSYLBGxRqCY--kgqWzKFxkYS9zMaozuman_AXcKrs0</recordid><startdate>20071201</startdate><enddate>20071201</enddate><creator>Okada, Fumito</creator><creator>Ando, Yumiko</creator><creator>Yoshitake, Sachie</creator><creator>Ono, Asami</creator><creator>Tanoue, Shuichi</creator><creator>Matsumoto, Shunro</creator><creator>Wakisaka, Masaki</creator><creator>Maeda, Toru</creator><creator>Mori, Hiromu</creator><general>Elsevier Inc</general><general>American College of Chest Physicians</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20071201</creationdate><title>Clinical/Pathologic Correlations in 553 Patients With Primary Centrilobular Findings on High-Resolution CT Scan of the Thorax</title><author>Okada, Fumito ; Ando, Yumiko ; Yoshitake, Sachie ; Ono, Asami ; Tanoue, Shuichi ; Matsumoto, Shunro ; Wakisaka, Masaki ; Maeda, Toru ; Mori, Hiromu</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c410t-7eab67c61e94d139b9530e314dc309b255c694d6b8abfe55af17f93effead5013</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>airway infection</topic><topic>Biological and medical sciences</topic><topic>Biopsy</topic><topic>bronchiolitis</topic><topic>Cardiology. Vascular system</topic><topic>Chronic obstructive pulmonary disease, asthma</topic><topic>CT scan</topic><topic>Diagnosis, Differential</topic><topic>Female</topic><topic>Humans</topic><topic>Lung Diseases - diagnostic imaging</topic><topic>Lung Diseases - microbiology</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Pneumology</topic><topic>Radiography, Thoracic</topic><topic>Retrospective Studies</topic><topic>Tomography, X-Ray Computed</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Okada, Fumito</creatorcontrib><creatorcontrib>Ando, Yumiko</creatorcontrib><creatorcontrib>Yoshitake, Sachie</creatorcontrib><creatorcontrib>Ono, Asami</creatorcontrib><creatorcontrib>Tanoue, Shuichi</creatorcontrib><creatorcontrib>Matsumoto, Shunro</creatorcontrib><creatorcontrib>Wakisaka, Masaki</creatorcontrib><creatorcontrib>Maeda, Toru</creatorcontrib><creatorcontrib>Mori, Hiromu</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Chest</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Okada, Fumito</au><au>Ando, Yumiko</au><au>Yoshitake, Sachie</au><au>Ono, Asami</au><au>Tanoue, Shuichi</au><au>Matsumoto, Shunro</au><au>Wakisaka, Masaki</au><au>Maeda, Toru</au><au>Mori, Hiromu</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Clinical/Pathologic Correlations in 553 Patients With Primary Centrilobular Findings on High-Resolution CT Scan of the Thorax</atitle><jtitle>Chest</jtitle><addtitle>Chest</addtitle><date>2007-12-01</date><risdate>2007</risdate><volume>132</volume><issue>6</issue><spage>1939</spage><epage>1948</epage><pages>1939-1948</pages><issn>0012-3692</issn><eissn>1931-3543</eissn><coden>CHETBF</coden><abstract>Clinical/pathologic correlations in patients with high-resolution CT (HRCT) scan findings presenting with two patterns of centrilobular opacity remain unclear.
Chest HRCT scans in 553 patients with predominant centrilobular opacities or preferential centrilobular disease were retrospectively evaluated. In 141 patients who underwent biopsy, CT scan images were compared with actual specimens.
Centrilobular nodules with a tree-in-bud appearance and bronchial wall thickening were observed in most patients who were carriers of human T-lymphotropic virus type 1 (88 patients and 57 of 99 patients, respectively), Mycoplasma pneumoniae pneumonia (44 patients and 45 of 52 patients, respectively), Mycobacterium tuberculosis (38 patients and 37 of 52 patients, respectively), Mycobacterium avium-intracellulare complex (22 patients and 27 of 37 patients, respectively), Mycobacterium kansasii (27 patients and 19 of 33 patients, respectively), allergic bronchopulmonary aspergillosis (6 patients and 7 of 9 patients, respectively), diffuse panbronchiolitis (12 patients and 10 of 12 patients, respectively), and diffuse aspiration bronchiolitis (12 patients and 12 of 13 patients, respectively). On the other hand, ill-defined centrilobular nodules of ground-glass attenuation were frequently seen in patients with subacute hypersensitivity pneumonitis (all 15 patients), metastatic calcification (all 4 patients), Churg-Strauss syndrome (4 of 12 patients), microscopic polyangiitis (27 of 48 patients), systemic lupus erythematosus (7 of 8 patients), and respiratory bronchiolitis-associated interstitial lung disease (all 8 patients). Pathologically, the tree-in-bud appearance correlated well with the plugging of small airways with mucous, pus, or fluid; dilated bronchioles; and bronchiolar wall thickening. Ill-defined centrilobular nodules represented peribronchiolar inflammation or the deposition of hemorrhagic materials.
Knowledge of the two centrilobular patterns is of proven worth for generating differential diagnoses and is of particular value in suggesting a likely infectious etiology in cases with tree-in-bud appearance.</abstract><cop>Northbrook, IL</cop><pub>Elsevier Inc</pub><pmid>18079227</pmid><doi>10.1378/chest.07-0482</doi><tpages>10</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0012-3692 |
| ispartof | Chest, 2007-12, Vol.132 (6), p.1939-1948 |
| issn | 0012-3692 1931-3543 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_69058537 |
| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Adolescent Adult Aged Aged, 80 and over airway infection Biological and medical sciences Biopsy bronchiolitis Cardiology. Vascular system Chronic obstructive pulmonary disease, asthma CT scan Diagnosis, Differential Female Humans Lung Diseases - diagnostic imaging Lung Diseases - microbiology Male Medical sciences Middle Aged Pneumology Radiography, Thoracic Retrospective Studies Tomography, X-Ray Computed |
| title | Clinical/Pathologic Correlations in 553 Patients With Primary Centrilobular Findings on High-Resolution CT Scan of the Thorax |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-22T21%3A29%3A22IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Clinical/Pathologic%20Correlations%20in%20553%20Patients%20With%20Primary%20Centrilobular%20Findings%20on%20High-Resolution%20CT%20Scan%20of%20the%20Thorax&rft.jtitle=Chest&rft.au=Okada,%20Fumito&rft.date=2007-12-01&rft.volume=132&rft.issue=6&rft.spage=1939&rft.epage=1948&rft.pages=1939-1948&rft.issn=0012-3692&rft.eissn=1931-3543&rft.coden=CHETBF&rft_id=info:doi/10.1378/chest.07-0482&rft_dat=%3Cproquest_cross%3E69058537%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=69058537&rft_id=info:pmid/18079227&rft_els_id=S0012369215524707&rfr_iscdi=true |