Pulmonary tuberculosis in allogeneic stem cell transplant recipients
Mycobacterium tuberculosis is a serious, but rare infectious complication after allogeneic bone marrow transplantation. Tuberculosis is a major problem in South East Asia, particularly in India and Pakistan. We describe here infection due to mycobacterium tuberculosis in four patients after allogene...
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| Veröffentlicht in: | Journal of the Pakistan Medical Association 2007-11, Vol.57 (11), p.567-569 |
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| container_title | Journal of the Pakistan Medical Association |
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| creator | ULLAH, Khalil RAZA, Shahida AHMED, Parvez TARIQ MAHMOOD SATTI IKRAM, Aamir CHAUDHRY, Qamar-Un-Nisa MUHAMMAD KHALID KAMAL FARRUKH MAHMOOD AKHTAR |
| description | Mycobacterium tuberculosis is a serious, but rare infectious complication after allogeneic bone marrow transplantation. Tuberculosis is a major problem in South East Asia, particularly in India and Pakistan. We describe here infection due to mycobacterium tuberculosis in four patients after allogeneic stem cell transplantation (Allo SCT). The diagnosis was made on the bases of clinical findings, sputum / blood / pleural and pericardial fluids / broncho alveolar lavage (BAL) and tissue biopsy examination. Anti tuberculosis therapy (ATT) was started immediately after diagnosis. Three patients responded to antituberculosis therapy, where as one patient developed severe infective respiratory complications and died at six months post transplant. Mycobacterial infection should be considered in patients post allo SCT with unexplained fever, cough or pleuritic chest pain. These patients at diagnosis should be promptly treated with ATT. |
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Tuberculosis is a major problem in South East Asia, particularly in India and Pakistan. We describe here infection due to mycobacterium tuberculosis in four patients after allogeneic stem cell transplantation (Allo SCT). The diagnosis was made on the bases of clinical findings, sputum / blood / pleural and pericardial fluids / broncho alveolar lavage (BAL) and tissue biopsy examination. Anti tuberculosis therapy (ATT) was started immediately after diagnosis. Three patients responded to antituberculosis therapy, where as one patient developed severe infective respiratory complications and died at six months post transplant. Mycobacterial infection should be considered in patients post allo SCT with unexplained fever, cough or pleuritic chest pain. These patients at diagnosis should be promptly treated with ATT.</description><identifier>ISSN: 0030-9982</identifier><identifier>PMID: 18062526</identifier><identifier>CODEN: JJPAD4</identifier><language>eng</language><publisher>Karachi: Pakistan Medical Association</publisher><subject>Adolescent ; Adult ; Antitubercular Agents - therapeutic use ; Bacterial diseases ; Bacterial diseases of the respiratory system ; Biological and medical sciences ; Child ; Child, Preschool ; General aspects ; Human bacterial diseases ; Humans ; Infectious diseases ; Male ; Medical sciences ; Risk Factors ; Stem Cell Transplantation - adverse effects ; Transplantation ; Transplantation, Homologous - adverse effects ; Tuberculosis and atypical mycobacterial infections ; Tuberculosis, Pulmonary - drug therapy ; Tuberculosis, Pulmonary - etiology</subject><ispartof>Journal of the Pakistan Medical Association, 2007-11, Vol.57 (11), p.567-569</ispartof><rights>2008 INIST-CNRS</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=20167700$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18062526$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>ULLAH, Khalil</creatorcontrib><creatorcontrib>RAZA, Shahida</creatorcontrib><creatorcontrib>AHMED, Parvez</creatorcontrib><creatorcontrib>TARIQ MAHMOOD SATTI</creatorcontrib><creatorcontrib>IKRAM, Aamir</creatorcontrib><creatorcontrib>CHAUDHRY, Qamar-Un-Nisa</creatorcontrib><creatorcontrib>MUHAMMAD KHALID KAMAL</creatorcontrib><creatorcontrib>FARRUKH MAHMOOD AKHTAR</creatorcontrib><title>Pulmonary tuberculosis in allogeneic stem cell transplant recipients</title><title>Journal of the Pakistan Medical Association</title><addtitle>J Pak Med Assoc</addtitle><description>Mycobacterium tuberculosis is a serious, but rare infectious complication after allogeneic bone marrow transplantation. Tuberculosis is a major problem in South East Asia, particularly in India and Pakistan. We describe here infection due to mycobacterium tuberculosis in four patients after allogeneic stem cell transplantation (Allo SCT). The diagnosis was made on the bases of clinical findings, sputum / blood / pleural and pericardial fluids / broncho alveolar lavage (BAL) and tissue biopsy examination. Anti tuberculosis therapy (ATT) was started immediately after diagnosis. Three patients responded to antituberculosis therapy, where as one patient developed severe infective respiratory complications and died at six months post transplant. Mycobacterial infection should be considered in patients post allo SCT with unexplained fever, cough or pleuritic chest pain. These patients at diagnosis should be promptly treated with ATT.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Antitubercular Agents - therapeutic use</subject><subject>Bacterial diseases</subject><subject>Bacterial diseases of the respiratory system</subject><subject>Biological and medical sciences</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>General aspects</subject><subject>Human bacterial diseases</subject><subject>Humans</subject><subject>Infectious diseases</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Risk Factors</subject><subject>Stem Cell Transplantation - adverse effects</subject><subject>Transplantation</subject><subject>Transplantation, Homologous - adverse effects</subject><subject>Tuberculosis and atypical mycobacterial infections</subject><subject>Tuberculosis, Pulmonary - drug therapy</subject><subject>Tuberculosis, Pulmonary - etiology</subject><issn>0030-9982</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kD1PxDAQRF2AODj4C8gNdJHWvnMSl-j4lE6CAupoY2-QkeOErFPw7wnioJrmaTRvjsQpwAYKa2u9EmfMHwC6NAAnYqVqKLXR5am4fZljPyScvmSeW5rcHAcOLEOSGOPwTomCk5ypl45ilHnCxGPElOVELoyBUuZzcdxhZLo45Fq83d-97h6L_fPD0-5mX4zKbHNhSaHvnDZo69IrMLUHVUJNWlFLiJocGKNtW-mOKo92q7W1gB43yoCvNmtx_ds7TsPnTJybPvDPLEw0zNyUFowCBQt4eQDntiffjFPoF8Xmz3sBrg4AssPYLVYu8D-nl11Vtdz3DSKyYLw</recordid><startdate>200711</startdate><enddate>200711</enddate><creator>ULLAH, Khalil</creator><creator>RAZA, Shahida</creator><creator>AHMED, Parvez</creator><creator>TARIQ MAHMOOD SATTI</creator><creator>IKRAM, Aamir</creator><creator>CHAUDHRY, Qamar-Un-Nisa</creator><creator>MUHAMMAD KHALID KAMAL</creator><creator>FARRUKH MAHMOOD AKHTAR</creator><general>Pakistan Medical Association</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>200711</creationdate><title>Pulmonary tuberculosis in allogeneic stem cell transplant recipients</title><author>ULLAH, Khalil ; RAZA, Shahida ; AHMED, Parvez ; TARIQ MAHMOOD SATTI ; IKRAM, Aamir ; CHAUDHRY, Qamar-Un-Nisa ; MUHAMMAD KHALID KAMAL ; FARRUKH MAHMOOD AKHTAR</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p154t-9e1adfc25a986d1058d01608e21ebeaa2ec05529b72fe7da9422990ada3150d73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Antitubercular Agents - therapeutic use</topic><topic>Bacterial diseases</topic><topic>Bacterial diseases of the respiratory system</topic><topic>Biological and medical sciences</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>General aspects</topic><topic>Human bacterial diseases</topic><topic>Humans</topic><topic>Infectious diseases</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Risk Factors</topic><topic>Stem Cell Transplantation - adverse effects</topic><topic>Transplantation</topic><topic>Transplantation, Homologous - adverse effects</topic><topic>Tuberculosis and atypical mycobacterial infections</topic><topic>Tuberculosis, Pulmonary - drug therapy</topic><topic>Tuberculosis, Pulmonary - etiology</topic><toplevel>online_resources</toplevel><creatorcontrib>ULLAH, Khalil</creatorcontrib><creatorcontrib>RAZA, Shahida</creatorcontrib><creatorcontrib>AHMED, Parvez</creatorcontrib><creatorcontrib>TARIQ MAHMOOD SATTI</creatorcontrib><creatorcontrib>IKRAM, Aamir</creatorcontrib><creatorcontrib>CHAUDHRY, Qamar-Un-Nisa</creatorcontrib><creatorcontrib>MUHAMMAD KHALID KAMAL</creatorcontrib><creatorcontrib>FARRUKH MAHMOOD AKHTAR</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of the Pakistan Medical Association</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>ULLAH, Khalil</au><au>RAZA, Shahida</au><au>AHMED, Parvez</au><au>TARIQ MAHMOOD SATTI</au><au>IKRAM, Aamir</au><au>CHAUDHRY, Qamar-Un-Nisa</au><au>MUHAMMAD KHALID KAMAL</au><au>FARRUKH MAHMOOD AKHTAR</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Pulmonary tuberculosis in allogeneic stem cell transplant recipients</atitle><jtitle>Journal of the Pakistan Medical Association</jtitle><addtitle>J Pak Med Assoc</addtitle><date>2007-11</date><risdate>2007</risdate><volume>57</volume><issue>11</issue><spage>567</spage><epage>569</epage><pages>567-569</pages><issn>0030-9982</issn><coden>JJPAD4</coden><abstract>Mycobacterium tuberculosis is a serious, but rare infectious complication after allogeneic bone marrow transplantation. Tuberculosis is a major problem in South East Asia, particularly in India and Pakistan. We describe here infection due to mycobacterium tuberculosis in four patients after allogeneic stem cell transplantation (Allo SCT). The diagnosis was made on the bases of clinical findings, sputum / blood / pleural and pericardial fluids / broncho alveolar lavage (BAL) and tissue biopsy examination. Anti tuberculosis therapy (ATT) was started immediately after diagnosis. Three patients responded to antituberculosis therapy, where as one patient developed severe infective respiratory complications and died at six months post transplant. Mycobacterial infection should be considered in patients post allo SCT with unexplained fever, cough or pleuritic chest pain. These patients at diagnosis should be promptly treated with ATT.</abstract><cop>Karachi</cop><pub>Pakistan Medical Association</pub><pmid>18062526</pmid><tpages>3</tpages></addata></record> |
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| ispartof | Journal of the Pakistan Medical Association, 2007-11, Vol.57 (11), p.567-569 |
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| source | MEDLINE; DOAJ Directory of Open Access Journals; EZB-FREE-00999 freely available EZB journals |
| subjects | Adolescent Adult Antitubercular Agents - therapeutic use Bacterial diseases Bacterial diseases of the respiratory system Biological and medical sciences Child Child, Preschool General aspects Human bacterial diseases Humans Infectious diseases Male Medical sciences Risk Factors Stem Cell Transplantation - adverse effects Transplantation Transplantation, Homologous - adverse effects Tuberculosis and atypical mycobacterial infections Tuberculosis, Pulmonary - drug therapy Tuberculosis, Pulmonary - etiology |
| title | Pulmonary tuberculosis in allogeneic stem cell transplant recipients |
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