Immunological properties of human embryonic stem cell-derived oligodendrocyte progenitor cells

Abstract A major concern in the use of allotransplantation of human embryonic stem cell (hESC)-based therapies is the possibility of allogeneic rejection by the host's immune system. In this report, we determined the immunological properties of hESC-derived oligodendrocyte progenitor cells (OPC...

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Veröffentlicht in:	Journal of neuroimmunology 2007-12, Vol.192 (1), p.134-144
Hauptverfasser:	Okamura, Ross M, Lebkowski, Jane, Au, Melinda, Priest, Catherine A, Denham, Jerrod, Majumdar, Anish S
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergy and Immunology Allogenicity Animals Cell Differentiation Cells, Cultured Cytokines - analysis DNA-Binding Proteins - deficiency Embryonic stem cells Embryonic Stem Cells - immunology Enzyme-Linked Immunosorbent Assay - methods Fetus Flow Cytometry - methods Humans Mice Mice, Knockout Mice, SCID Neu5Gc Neurology Oligodendrocyte progenitors Oligodendroglia - immunology Sialic Acids - metabolism Spinal Cord - metabolism Stem Cell Transplantation - methods T-Lymphocytes - drug effects T-Lymphocytes - immunology
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