Effect of Egyptian Propolis on the Susceptibility of LDL to Oxidative Modification and its Antiviral Activity with Special Emphasis on Chemical Composition

The antioxidant activity of eight Egyptian propolis samples from different localities was evaluated by the antioxidative potential and capacity of the DPPH-ESR signal, superoxide anion generated in the xanthine-xanthine oxidase (XOD) system and low density lipoprotein (LDL) peroxidation assay. As, F...

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Veröffentlicht in:Zeitschrift für Naturforschung C. A journal of biosciences 2007-09, Vol.62 (9), p.645-655
Hauptverfasser: El-Hadya, Faten K. Abd, Hegazi, Ahmed G., Wollenweber, Eckhard
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container_issue 9
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container_title Zeitschrift für Naturforschung C. A journal of biosciences
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creator El-Hadya, Faten K. Abd
Hegazi, Ahmed G.
Wollenweber, Eckhard
description The antioxidant activity of eight Egyptian propolis samples from different localities was evaluated by the antioxidative potential and capacity of the DPPH-ESR signal, superoxide anion generated in the xanthine-xanthine oxidase (XOD) system and low density lipoprotein (LDL) peroxidation assay. As, F, Is and D samples showed the highest antioxidative capacity and potential, respectively. The El, IsR, Is, D and So samples exhibited highly significant antioxidant activity in the XOD system and in LDL peroxidation assays. The antiviral activity of propolis samples was investigated. They showed variations in their activity; sample D induced the highest antiviral activity against Newcastle disease virus and infectious bursal disease virus. 42 Polyphenolic compounds were identified by HPLC; 13 aromatic acids, esters and alcohols were present, 29 flavonoids were identified, 6 of them being new to propolis.
doi_str_mv 10.1515/znc-2007-9-1004
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source MEDLINE; EZB-FREE-00999 freely available EZB journals
subjects Antiviral
Antiviral Agents - chemistry
Antiviral Agents - pharmacology
Chromatography, High Pressure Liquid
Egypt
Electron Spin Resonance Spectroscopy
Humans
Infectious bursal disease virus - drug effects
Kinetics
LDL Peroxidation
Lipoproteins, LDL - blood
Lipoproteins, LDL - drug effects
Lipoproteins, LDL - metabolism
Newcastle disease virus - drug effects
Polyphenolics
Propolis - chemistry
Propolis - isolation & purification
Propolis - pharmacology
Superoxides - metabolism
title Effect of Egyptian Propolis on the Susceptibility of LDL to Oxidative Modification and its Antiviral Activity with Special Emphasis on Chemical Composition
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