Effect of Egyptian Propolis on the Susceptibility of LDL to Oxidative Modification and its Antiviral Activity with Special Emphasis on Chemical Composition
The antioxidant activity of eight Egyptian propolis samples from different localities was evaluated by the antioxidative potential and capacity of the DPPH-ESR signal, superoxide anion generated in the xanthine-xanthine oxidase (XOD) system and low density lipoprotein (LDL) peroxidation assay. As, F...
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Veröffentlicht in: | Zeitschrift für Naturforschung C. A journal of biosciences 2007-09, Vol.62 (9), p.645-655 |
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creator | El-Hadya, Faten K. Abd Hegazi, Ahmed G. Wollenweber, Eckhard |
description | The antioxidant activity of eight Egyptian propolis samples from different localities was evaluated by the antioxidative potential and capacity of the DPPH-ESR signal, superoxide anion generated in the xanthine-xanthine oxidase (XOD) system and low density lipoprotein (LDL) peroxidation assay. As, F, Is and D samples showed the highest antioxidative capacity and potential, respectively. The El, IsR, Is, D and So samples exhibited highly significant antioxidant activity in the XOD system and in LDL peroxidation assays.
The antiviral activity of propolis samples was investigated. They showed variations in their activity; sample D induced the highest antiviral activity against Newcastle disease virus and infectious bursal disease virus.
42 Polyphenolic compounds were identified by HPLC; 13 aromatic acids, esters and alcohols were present, 29 flavonoids were identified, 6 of them being new to propolis. |
doi_str_mv | 10.1515/znc-2007-9-1004 |
format | Article |
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The antiviral activity of propolis samples was investigated. They showed variations in their activity; sample D induced the highest antiviral activity against Newcastle disease virus and infectious bursal disease virus.
42 Polyphenolic compounds were identified by HPLC; 13 aromatic acids, esters and alcohols were present, 29 flavonoids were identified, 6 of them being new to propolis.</description><identifier>ISSN: 0939-5075</identifier><identifier>EISSN: 1865-7125</identifier><identifier>DOI: 10.1515/znc-2007-9-1004</identifier><identifier>PMID: 18069235</identifier><language>eng</language><publisher>Germany: Verlag der Zeitschrift für Naturforschung</publisher><subject>Antiviral ; Antiviral Agents - chemistry ; Antiviral Agents - pharmacology ; Chromatography, High Pressure Liquid ; Egypt ; Electron Spin Resonance Spectroscopy ; Humans ; Infectious bursal disease virus - drug effects ; Kinetics ; LDL Peroxidation ; Lipoproteins, LDL - blood ; Lipoproteins, LDL - drug effects ; Lipoproteins, LDL - metabolism ; Newcastle disease virus - drug effects ; Polyphenolics ; Propolis - chemistry ; Propolis - isolation & purification ; Propolis - pharmacology ; Superoxides - metabolism</subject><ispartof>Zeitschrift für Naturforschung C. A journal of biosciences, 2007-09, Vol.62 (9), p.645-655</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c393t-4cc8eb2e9946289f520c5b42c2ca1ad0a8e3eccbb0aa6fdbcb1e8aef801f50113</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27923,27924</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18069235$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>El-Hadya, Faten K. Abd</creatorcontrib><creatorcontrib>Hegazi, Ahmed G.</creatorcontrib><creatorcontrib>Wollenweber, Eckhard</creatorcontrib><title>Effect of Egyptian Propolis on the Susceptibility of LDL to Oxidative Modification and its Antiviral Activity with Special Emphasis on Chemical Composition</title><title>Zeitschrift für Naturforschung C. A journal of biosciences</title><addtitle>Z Naturforsch C</addtitle><description>The antioxidant activity of eight Egyptian propolis samples from different localities was evaluated by the antioxidative potential and capacity of the DPPH-ESR signal, superoxide anion generated in the xanthine-xanthine oxidase (XOD) system and low density lipoprotein (LDL) peroxidation assay. As, F, Is and D samples showed the highest antioxidative capacity and potential, respectively. The El, IsR, Is, D and So samples exhibited highly significant antioxidant activity in the XOD system and in LDL peroxidation assays.
The antiviral activity of propolis samples was investigated. They showed variations in their activity; sample D induced the highest antiviral activity against Newcastle disease virus and infectious bursal disease virus.
42 Polyphenolic compounds were identified by HPLC; 13 aromatic acids, esters and alcohols were present, 29 flavonoids were identified, 6 of them being new to propolis.</description><subject>Antiviral</subject><subject>Antiviral Agents - chemistry</subject><subject>Antiviral Agents - pharmacology</subject><subject>Chromatography, High Pressure Liquid</subject><subject>Egypt</subject><subject>Electron Spin Resonance Spectroscopy</subject><subject>Humans</subject><subject>Infectious bursal disease virus - drug effects</subject><subject>Kinetics</subject><subject>LDL Peroxidation</subject><subject>Lipoproteins, LDL - blood</subject><subject>Lipoproteins, LDL - drug effects</subject><subject>Lipoproteins, LDL - metabolism</subject><subject>Newcastle disease virus - drug effects</subject><subject>Polyphenolics</subject><subject>Propolis - chemistry</subject><subject>Propolis - isolation & purification</subject><subject>Propolis - pharmacology</subject><subject>Superoxides - metabolism</subject><issn>0939-5075</issn><issn>1865-7125</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kUFv1DAQhS0EotuWMzfkE7dQ24md-MZqu1CkrYrUcrYcZ9x1lcTBdijbv8KfxdGuxInTjD3fe6PRQ-g9JZ8op_zqZTQFI6QuZEEJqV6hFW0EL2rK-Gu0IrKUBSc1P0PnMT4RUgpe87fojDZESFbyFfqztRZMwt7i7eNhSk6P-Hvwk-9dxH7EaQ_4fo4G8qh1vUuHBd1d73Dy-O6363RyvwDf-s5ZZ_Ija_TYYZciXo955oLu8dosXdY-u7TH9xMYl3-3w7TX8bhns4ch63u88cPko1uMLtEbq_sI7071Av34sn3Y3BS7u6_fNutdYUpZpqIypoGWgZSVYI20nBHD24oZZjTVHdENlGBM2xKthe1a01JoNNiGUMsJpeUF-nj0nYL_OUNManD54r7XI_g5KiFJVUvBMnh1BE3wMQawagpu0OGgKFFLHirnoZY8lFRLHlnx4WQ9twN0__hTABn4fASedZ8gdPAY5kNu1JOfw5iv_p-1YEsVFS__AhOAn4k</recordid><startdate>20070901</startdate><enddate>20070901</enddate><creator>El-Hadya, Faten K. 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Abd</creatorcontrib><creatorcontrib>Hegazi, Ahmed G.</creatorcontrib><creatorcontrib>Wollenweber, Eckhard</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Zeitschrift für Naturforschung C. A journal of biosciences</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>El-Hadya, Faten K. Abd</au><au>Hegazi, Ahmed G.</au><au>Wollenweber, Eckhard</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effect of Egyptian Propolis on the Susceptibility of LDL to Oxidative Modification and its Antiviral Activity with Special Emphasis on Chemical Composition</atitle><jtitle>Zeitschrift für Naturforschung C. A journal of biosciences</jtitle><addtitle>Z Naturforsch C</addtitle><date>2007-09-01</date><risdate>2007</risdate><volume>62</volume><issue>9</issue><spage>645</spage><epage>655</epage><pages>645-655</pages><issn>0939-5075</issn><eissn>1865-7125</eissn><abstract>The antioxidant activity of eight Egyptian propolis samples from different localities was evaluated by the antioxidative potential and capacity of the DPPH-ESR signal, superoxide anion generated in the xanthine-xanthine oxidase (XOD) system and low density lipoprotein (LDL) peroxidation assay. As, F, Is and D samples showed the highest antioxidative capacity and potential, respectively. The El, IsR, Is, D and So samples exhibited highly significant antioxidant activity in the XOD system and in LDL peroxidation assays.
The antiviral activity of propolis samples was investigated. They showed variations in their activity; sample D induced the highest antiviral activity against Newcastle disease virus and infectious bursal disease virus.
42 Polyphenolic compounds were identified by HPLC; 13 aromatic acids, esters and alcohols were present, 29 flavonoids were identified, 6 of them being new to propolis.</abstract><cop>Germany</cop><pub>Verlag der Zeitschrift für Naturforschung</pub><pmid>18069235</pmid><doi>10.1515/znc-2007-9-1004</doi><tpages>11</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Antiviral Antiviral Agents - chemistry Antiviral Agents - pharmacology Chromatography, High Pressure Liquid Egypt Electron Spin Resonance Spectroscopy Humans Infectious bursal disease virus - drug effects Kinetics LDL Peroxidation Lipoproteins, LDL - blood Lipoproteins, LDL - drug effects Lipoproteins, LDL - metabolism Newcastle disease virus - drug effects Polyphenolics Propolis - chemistry Propolis - isolation & purification Propolis - pharmacology Superoxides - metabolism |
title | Effect of Egyptian Propolis on the Susceptibility of LDL to Oxidative Modification and its Antiviral Activity with Special Emphasis on Chemical Composition |
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