Subtype-specific activation of estrogen receptors by a special extract of Rheum rhaponticum (ERr 731 ®), its aglycones and structurally related compounds in U2OS human osteosarcoma cells

The special extract ERr 731 ® from the roots of Rheum rhaponticum is the major constituent of Phytoestrol ® N which is used for the alleviation of menopausal symptoms. Recently, we demonstrated that ERr 731 ® and its aglycones trans-rhapontigenin and desoxyrhapontigenin as single test substances do...

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