Plasticity of Rodent and Human Hair Follicle Dermal Cells:Implications for Cell Therapy and Tissue Engineering

The dermal components of the hair follicle exhibit a number of stem cell properties, including regenerative potential, roles in wound healing and the ability to produce a functional dermis. Here we examine the stem cell phenomenon of plasticity, focusing on recent observations of in vitro plasticity...

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Veröffentlicht in:The Journal of investigative dermatology symposium proceedings 2005-12, Vol.10 (3), p.180-183
Hauptverfasser: Richardson, Gavin D., Arnott, Elisabeth C., Whitehouse, Claire J., Lawrence, Clifford M., Reynolds, Amanda J., Hole, Nicholas, Jahoda, Colin A.B.
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container_issue 3
container_start_page 180
container_title The Journal of investigative dermatology symposium proceedings
container_volume 10
creator Richardson, Gavin D.
Arnott, Elisabeth C.
Whitehouse, Claire J.
Lawrence, Clifford M.
Reynolds, Amanda J.
Hole, Nicholas
Jahoda, Colin A.B.
description The dermal components of the hair follicle exhibit a number of stem cell properties, including regenerative potential, roles in wound healing and the ability to produce a functional dermis. Here we examine the stem cell phenomenon of plasticity, focusing on recent observations of in vitro plasticity of dermal papilla and sheath cells, including previously unpublished data of neuronal-like differentiation. We then briefly address the implications of the stem cell potential of hair follicle dermal cells for the field of tissue engineering.
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subjects Animals
Cell Differentiation - physiology
Cell- and Tissue-Based Therapy
dermal papilla
dermal sheath
Dermis - cytology
Dermis - physiology
hair follicle
Hair Follicle - cytology
Hair Follicle - physiology
Humans
plasticity
Rats
stem cells
Stem Cells - physiology
Tissue Engineering
title Plasticity of Rodent and Human Hair Follicle Dermal Cells:Implications for Cell Therapy and Tissue Engineering
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