Effect of genetic polymorphism of MTNR1A gene on adolescent idiopathic scoliosis

To investigate whether the MTNR1A gene promotor polymorphism (rs2119882) are associated with the occurrence or curve severity of adolescent idiopathic scoliosis (AIS). 226 AIS patients and 277 normal controls were recruited. The maximum Cobb angles were recorded in AIS patients. PCR-RFLP was used fo...

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Veröffentlicht in:	Chung-hua wai kʿo tsa chih 2007-09, Vol.45 (18), p.1264-1266
Hauptverfasser:	Qiu, Xu-sheng, Tang, Leung-sang, Yeung, Hiu-yan, Kwok, Hoi-kei, Lee, Kwong-man, Qin, Ling, Qiu, Yong, Cheng, Chun-yiu
Format:	Artikel
Sprache:	chi
Schlagworte:	Adolescent Adult Child Female Gene Frequency Genetic Predisposition to Disease Genotype Humans Male Polymerase Chain Reaction Polymorphism, Genetic Polymorphism, Restriction Fragment Length Receptor, Melatonin, MT1 - genetics Scoliosis - genetics
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