Termination Factor-Mediated DNA Loop between Termination and Initiation Sites Drives Mitochondrial rRNA Synthesis

The human mitochondrial transcription termination factor mTERF plays a central role in the control of heavy-strand rDNA transcription by promoting initiation, besides termination, of this transcription. However, until now, the mechanism underlying this stimulation of transcription by mTERF was not u...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Cell 2005-12, Vol.123 (7), p.1227-1240
Hauptverfasser:	Martin, Miguel, Cho, Jaehyoung, Cesare, Anthony J., Griffith, Jack D., Attardi, Giuseppe
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell-Free System - chemistry Cell-Free System - metabolism DNA - chemistry HeLa Cells Humans Mitochondria - chemistry RNA - biosynthesis RNA - genetics RNA, Ribosomal - biosynthesis Telomeric Repeat Binding Protein 1 - genetics Telomeric Repeat Binding Protein 1 - metabolism Terminator Regions, Genetic - physiology Transcription Initiation Site - physiology Transcription, Genetic - physiology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!