Association of Complement Factor H and LOC387715 Genotypes with Response of Exudative Age-Related Macular Degeneration to Intravitreal Bevacizumab

Purpose To investigate whether there is an association between complement factor H (CFH) or LOC387715 genotypes with response to treatment with intravitreal bevacizumab for exudative age-related macular degeneration (AMD). Design Retrospective cohort study. Participants The study cohort consisted of...

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Veröffentlicht in:	Ophthalmology (Rochester, Minn.) Minn.), 2007-12, Vol.114 (12), p.2168-2173
Hauptverfasser:	Brantley, Milam A., MD, PhD, Fang, Amy M., MD, King, Jennifer M., BS, Tewari, Asheesh, MD, Kymes, Steven M., PhD, MHA, Shiels, Alan, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Angiogenesis Inhibitors - therapeutic use Antibodies, Monoclonal - therapeutic use Antibodies, Monoclonal, Humanized Bevacizumab Biological and medical sciences Choroidal Neovascularization - drug therapy Choroidal Neovascularization - genetics Complement Factor H - genetics Exudates and Transudates Female Fluorescein Angiography Genotype Humans Injections Macular Degeneration - drug therapy Macular Degeneration - genetics Male Medical sciences Miscellaneous Ophthalmology Pharmacogenetics Polymerase Chain Reaction Polymorphism, Single Nucleotide Proteins - genetics Retinopathies Retrospective Studies Vascular Endothelial Growth Factor A - antagonists & inhibitors Visual Acuity Vitreous Body
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