Signal transduction pathways associated with ATP‐induced proliferation of cell progenitors in the intact embryonic retina

ATP and ADP induce retinal cell proliferation through activation of PKC and extracellular signal‐regulated kinases (ERKs). Here, we characterized the effect of purinergic agonists on the turnover of phosphoinositides and activation of ERKs during development of the chick embryo retina. When intact r...

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Veröffentlicht in:	International journal of developmental neuroscience 2007-12, Vol.25 (8), p.499-508
Hauptverfasser:	Nunes, Patricia Helena Castro, Calaza, Karin da Costa, Albuquerque, Lidiane Martins, Fragel‐Madeira, Lucianne, Sholl‐Franco, Alfred, Ventura, Ana Lucia Marques
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Diphosphate - pharmacology Adenosine Triphosphate - pharmacology Animals Blotting, Western Bromodeoxyuridine Cell Count Cell Proliferation - drug effects Chick Embryo Chick retina DNA - biosynthesis ERK Immunohistochemistry Mitogen-Activated Protein Kinases - metabolism Nucleotides Organ Culture Techniques P2 receptors Phosphatidylinositols - metabolism Phosphoinositides Proliferation Receptors, Purinergic P2 - physiology Receptors, Purinergic P2Y1 Retina - cytology Retina - embryology Retina - metabolism Signal Transduction - physiology Stem Cells - metabolism Stem Cells - physiology Thymidine - metabolism Tissue Fixation Uridine Triphosphate - pharmacology
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