Primary Sclerosing Cholangitis and Uveitis: A Case Series

Purpose To report the cases of six patients with primary sclerosing cholangitis and uveitis. Design Retrospective observational case series. Methods Two index cases were identified from the Uveitis Clinic of the Casey Eye Institute, Oregon Health and Science University and another from the Portland...

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Veröffentlicht in:American journal of ophthalmology 2007-03, Vol.143 (3), p.534-536
Hauptverfasser: Hoang, Lani T., BS, Lim, Lyndell L., MBBS, FRANZCO, Walton, R. Christopher, MD, Goldstein, Debra A., MD, FRCS(C), Chalmers, Brent, MD, Rosenbaum, James T., MD
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container_end_page 536
container_issue 3
container_start_page 534
container_title American journal of ophthalmology
container_volume 143
creator Hoang, Lani T., BS
Lim, Lyndell L., MBBS, FRANZCO
Walton, R. Christopher, MD
Goldstein, Debra A., MD, FRCS(C)
Chalmers, Brent, MD
Rosenbaum, James T., MD
description Purpose To report the cases of six patients with primary sclerosing cholangitis and uveitis. Design Retrospective observational case series. Methods Two index cases were identified from the Uveitis Clinic of the Casey Eye Institute, Oregon Health and Science University and another from the Portland area. Additional cases were identified through a web-based survey of members of the American Uveitis Society. Results Three males and three females were identified. Five of six patients were diagnosed with uveitis prior to primary sclerosing cholangitis. Four had unilateral eye involvement. Five had insidious onset. All had persistent duration. Clinical course was chronic for three, recurrent for two, and chronic-recurrent in one. Vitreous inflammation was prominent in five. Conclusions Although the number of patients who were studied is limited, there appears to be an association between primary sclerosing cholangitis and uveitis. Further studies are required to confirm such an association.
doi_str_mv 10.1016/j.ajo.2006.09.055
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Christopher, MD ; Goldstein, Debra A., MD, FRCS(C) ; Chalmers, Brent, MD ; Rosenbaum, James T., MD</creator><creatorcontrib>Hoang, Lani T., BS ; Lim, Lyndell L., MBBS, FRANZCO ; Walton, R. Christopher, MD ; Goldstein, Debra A., MD, FRCS(C) ; Chalmers, Brent, MD ; Rosenbaum, James T., MD</creatorcontrib><description>Purpose To report the cases of six patients with primary sclerosing cholangitis and uveitis. Design Retrospective observational case series. Methods Two index cases were identified from the Uveitis Clinic of the Casey Eye Institute, Oregon Health and Science University and another from the Portland area. Additional cases were identified through a web-based survey of members of the American Uveitis Society. Results Three males and three females were identified. Five of six patients were diagnosed with uveitis prior to primary sclerosing cholangitis. Four had unilateral eye involvement. Five had insidious onset. All had persistent duration. Clinical course was chronic for three, recurrent for two, and chronic-recurrent in one. Vitreous inflammation was prominent in five. Conclusions Although the number of patients who were studied is limited, there appears to be an association between primary sclerosing cholangitis and uveitis. Further studies are required to confirm such an association.</description><identifier>ISSN: 0002-9394</identifier><identifier>EISSN: 1879-1891</identifier><identifier>DOI: 10.1016/j.ajo.2006.09.055</identifier><identifier>PMID: 17317411</identifier><identifier>CODEN: AJOPAA</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Adult ; Bile ; Biological and medical sciences ; Cholangitis, Sclerosing - complications ; Cholangitis, Sclerosing - diagnosis ; Chronic Disease ; Female ; Gastroenterology. Liver. Pancreas. Abdomen ; Humans ; Inflammatory bowel disease ; Liver ; Liver. Biliary tract. Portal circulation. Exocrine pancreas ; Male ; Medical sciences ; Middle Aged ; Miscellaneous ; Ophthalmology ; Other diseases. 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Christopher, MD</creatorcontrib><creatorcontrib>Goldstein, Debra A., MD, FRCS(C)</creatorcontrib><creatorcontrib>Chalmers, Brent, MD</creatorcontrib><creatorcontrib>Rosenbaum, James T., MD</creatorcontrib><title>Primary Sclerosing Cholangitis and Uveitis: A Case Series</title><title>American journal of ophthalmology</title><addtitle>Am J Ophthalmol</addtitle><description>Purpose To report the cases of six patients with primary sclerosing cholangitis and uveitis. Design Retrospective observational case series. Methods Two index cases were identified from the Uveitis Clinic of the Casey Eye Institute, Oregon Health and Science University and another from the Portland area. Additional cases were identified through a web-based survey of members of the American Uveitis Society. Results Three males and three females were identified. Five of six patients were diagnosed with uveitis prior to primary sclerosing cholangitis. Four had unilateral eye involvement. Five had insidious onset. All had persistent duration. Clinical course was chronic for three, recurrent for two, and chronic-recurrent in one. Vitreous inflammation was prominent in five. Conclusions Although the number of patients who were studied is limited, there appears to be an association between primary sclerosing cholangitis and uveitis. Further studies are required to confirm such an association.</description><subject>Adult</subject><subject>Bile</subject><subject>Biological and medical sciences</subject><subject>Cholangitis, Sclerosing - complications</subject><subject>Cholangitis, Sclerosing - diagnosis</subject><subject>Chronic Disease</subject><subject>Female</subject><subject>Gastroenterology. Liver. Pancreas. Abdomen</subject><subject>Humans</subject><subject>Inflammatory bowel disease</subject><subject>Liver</subject><subject>Liver. Biliary tract. Portal circulation. Exocrine pancreas</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Miscellaneous</subject><subject>Ophthalmology</subject><subject>Other diseases. Semiology</subject><subject>Recurrence</subject><subject>Retrospective Studies</subject><subject>Transplants &amp; implants</subject><subject>Uvea diseases</subject><subject>Uveitis - complications</subject><subject>Uveitis - diagnosis</subject><issn>0002-9394</issn><issn>1879-1891</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kVtr3DAQhUVpaTZJf0BfiqE0b3ZmrIulFgph6SUQaGGTZ6GVx6lcr51Iu4H8-8rswkIe-qQZ-M7ozBnG3iNUCKgu-8r1U1UDqApMBVK-YgvUjSlRG3zNFgBQl4YbccJOU-pzqxrRvGUn2HBsBOKCmd8xbFx8LlZ-oDilMN4Xyz_T4Mb7sA2pcGNb3D3RXH8uroqlS1SsKAZK5-xN54ZE7w7vGbv7_u12-bO8-fXjenl1U3qhxLbkhsvadZg73WhopQSqnXSdWq9bL50y2kippCcwxlCruFpnoRRaopdK8TN2sZ_7EKfHHaWt3YTkacgWadolqwxwVQPP4McXYD_t4pi9WVRCGAUoIFO4p3zeNkXq7MM-AYtg51Rtb3Oqdk7VgrE51az5cJi8W2-oPSoOMWbg0wFwybuhi270IR05rWupa525L3uOcmBPgaJNPtDoqQ2R_Na2U_ivja8v1H4IY8gf_qVnSsdtbaot2NV8_vn6kDdHnst_LxOl_g</recordid><startdate>20070301</startdate><enddate>20070301</enddate><creator>Hoang, Lani T., BS</creator><creator>Lim, Lyndell L., MBBS, FRANZCO</creator><creator>Walton, R. Christopher, MD</creator><creator>Goldstein, Debra A., MD, FRCS(C)</creator><creator>Chalmers, Brent, MD</creator><creator>Rosenbaum, James T., MD</creator><general>Elsevier Inc</general><general>Elsevier</general><general>Elsevier Limited</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope></search><sort><creationdate>20070301</creationdate><title>Primary Sclerosing Cholangitis and Uveitis: A Case Series</title><author>Hoang, Lani T., BS ; Lim, Lyndell L., MBBS, FRANZCO ; Walton, R. Christopher, MD ; Goldstein, Debra A., MD, FRCS(C) ; Chalmers, Brent, MD ; Rosenbaum, James T., MD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c464t-39352af1c468780d550e2a5af6bbdc5a69895565ce0999ed636b46454851c5663</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Adult</topic><topic>Bile</topic><topic>Biological and medical sciences</topic><topic>Cholangitis, Sclerosing - complications</topic><topic>Cholangitis, Sclerosing - diagnosis</topic><topic>Chronic Disease</topic><topic>Female</topic><topic>Gastroenterology. Liver. Pancreas. Abdomen</topic><topic>Humans</topic><topic>Inflammatory bowel disease</topic><topic>Liver</topic><topic>Liver. Biliary tract. Portal circulation. Exocrine pancreas</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Miscellaneous</topic><topic>Ophthalmology</topic><topic>Other diseases. 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subjects Adult
Bile
Biological and medical sciences
Cholangitis, Sclerosing - complications
Cholangitis, Sclerosing - diagnosis
Chronic Disease
Female
Gastroenterology. Liver. Pancreas. Abdomen
Humans
Inflammatory bowel disease
Liver
Liver. Biliary tract. Portal circulation. Exocrine pancreas
Male
Medical sciences
Middle Aged
Miscellaneous
Ophthalmology
Other diseases. Semiology
Recurrence
Retrospective Studies
Transplants & implants
Uvea diseases
Uveitis - complications
Uveitis - diagnosis
title Primary Sclerosing Cholangitis and Uveitis: A Case Series
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