Primary Sclerosing Cholangitis and Uveitis: A Case Series
Purpose To report the cases of six patients with primary sclerosing cholangitis and uveitis. Design Retrospective observational case series. Methods Two index cases were identified from the Uveitis Clinic of the Casey Eye Institute, Oregon Health and Science University and another from the Portland...
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Veröffentlicht in: | American journal of ophthalmology 2007-03, Vol.143 (3), p.534-536 |
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container_title | American journal of ophthalmology |
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creator | Hoang, Lani T., BS Lim, Lyndell L., MBBS, FRANZCO Walton, R. Christopher, MD Goldstein, Debra A., MD, FRCS(C) Chalmers, Brent, MD Rosenbaum, James T., MD |
description | Purpose To report the cases of six patients with primary sclerosing cholangitis and uveitis. Design Retrospective observational case series. Methods Two index cases were identified from the Uveitis Clinic of the Casey Eye Institute, Oregon Health and Science University and another from the Portland area. Additional cases were identified through a web-based survey of members of the American Uveitis Society. Results Three males and three females were identified. Five of six patients were diagnosed with uveitis prior to primary sclerosing cholangitis. Four had unilateral eye involvement. Five had insidious onset. All had persistent duration. Clinical course was chronic for three, recurrent for two, and chronic-recurrent in one. Vitreous inflammation was prominent in five. Conclusions Although the number of patients who were studied is limited, there appears to be an association between primary sclerosing cholangitis and uveitis. Further studies are required to confirm such an association. |
doi_str_mv | 10.1016/j.ajo.2006.09.055 |
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Christopher, MD ; Goldstein, Debra A., MD, FRCS(C) ; Chalmers, Brent, MD ; Rosenbaum, James T., MD</creator><creatorcontrib>Hoang, Lani T., BS ; Lim, Lyndell L., MBBS, FRANZCO ; Walton, R. Christopher, MD ; Goldstein, Debra A., MD, FRCS(C) ; Chalmers, Brent, MD ; Rosenbaum, James T., MD</creatorcontrib><description>Purpose To report the cases of six patients with primary sclerosing cholangitis and uveitis. Design Retrospective observational case series. Methods Two index cases were identified from the Uveitis Clinic of the Casey Eye Institute, Oregon Health and Science University and another from the Portland area. Additional cases were identified through a web-based survey of members of the American Uveitis Society. Results Three males and three females were identified. Five of six patients were diagnosed with uveitis prior to primary sclerosing cholangitis. Four had unilateral eye involvement. Five had insidious onset. All had persistent duration. Clinical course was chronic for three, recurrent for two, and chronic-recurrent in one. Vitreous inflammation was prominent in five. Conclusions Although the number of patients who were studied is limited, there appears to be an association between primary sclerosing cholangitis and uveitis. Further studies are required to confirm such an association.</description><identifier>ISSN: 0002-9394</identifier><identifier>EISSN: 1879-1891</identifier><identifier>DOI: 10.1016/j.ajo.2006.09.055</identifier><identifier>PMID: 17317411</identifier><identifier>CODEN: AJOPAA</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Adult ; Bile ; Biological and medical sciences ; Cholangitis, Sclerosing - complications ; Cholangitis, Sclerosing - diagnosis ; Chronic Disease ; Female ; Gastroenterology. Liver. Pancreas. Abdomen ; Humans ; Inflammatory bowel disease ; Liver ; Liver. Biliary tract. Portal circulation. Exocrine pancreas ; Male ; Medical sciences ; Middle Aged ; Miscellaneous ; Ophthalmology ; Other diseases. Semiology ; Recurrence ; Retrospective Studies ; Transplants & implants ; Uvea diseases ; Uveitis - complications ; Uveitis - diagnosis</subject><ispartof>American journal of ophthalmology, 2007-03, Vol.143 (3), p.534-536</ispartof><rights>Elsevier Inc.</rights><rights>2007 Elsevier Inc.</rights><rights>2007 INIST-CNRS</rights><rights>Copyright Elsevier Limited Mar 2007</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c464t-39352af1c468780d550e2a5af6bbdc5a69895565ce0999ed636b46454851c5663</citedby><cites>FETCH-LOGICAL-c464t-39352af1c468780d550e2a5af6bbdc5a69895565ce0999ed636b46454851c5663</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.ajo.2006.09.055$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=18825828$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17317411$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hoang, Lani T., BS</creatorcontrib><creatorcontrib>Lim, Lyndell L., MBBS, FRANZCO</creatorcontrib><creatorcontrib>Walton, R. Christopher, MD</creatorcontrib><creatorcontrib>Goldstein, Debra A., MD, FRCS(C)</creatorcontrib><creatorcontrib>Chalmers, Brent, MD</creatorcontrib><creatorcontrib>Rosenbaum, James T., MD</creatorcontrib><title>Primary Sclerosing Cholangitis and Uveitis: A Case Series</title><title>American journal of ophthalmology</title><addtitle>Am J Ophthalmol</addtitle><description>Purpose To report the cases of six patients with primary sclerosing cholangitis and uveitis. Design Retrospective observational case series. Methods Two index cases were identified from the Uveitis Clinic of the Casey Eye Institute, Oregon Health and Science University and another from the Portland area. Additional cases were identified through a web-based survey of members of the American Uveitis Society. Results Three males and three females were identified. Five of six patients were diagnosed with uveitis prior to primary sclerosing cholangitis. Four had unilateral eye involvement. Five had insidious onset. All had persistent duration. Clinical course was chronic for three, recurrent for two, and chronic-recurrent in one. Vitreous inflammation was prominent in five. Conclusions Although the number of patients who were studied is limited, there appears to be an association between primary sclerosing cholangitis and uveitis. Further studies are required to confirm such an association.</description><subject>Adult</subject><subject>Bile</subject><subject>Biological and medical sciences</subject><subject>Cholangitis, Sclerosing - complications</subject><subject>Cholangitis, Sclerosing - diagnosis</subject><subject>Chronic Disease</subject><subject>Female</subject><subject>Gastroenterology. Liver. Pancreas. Abdomen</subject><subject>Humans</subject><subject>Inflammatory bowel disease</subject><subject>Liver</subject><subject>Liver. Biliary tract. Portal circulation. Exocrine pancreas</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Miscellaneous</subject><subject>Ophthalmology</subject><subject>Other diseases. Semiology</subject><subject>Recurrence</subject><subject>Retrospective Studies</subject><subject>Transplants & implants</subject><subject>Uvea diseases</subject><subject>Uveitis - complications</subject><subject>Uveitis - diagnosis</subject><issn>0002-9394</issn><issn>1879-1891</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kVtr3DAQhUVpaTZJf0BfiqE0b3ZmrIulFgph6SUQaGGTZ6GVx6lcr51Iu4H8-8rswkIe-qQZ-M7ozBnG3iNUCKgu-8r1U1UDqApMBVK-YgvUjSlRG3zNFgBQl4YbccJOU-pzqxrRvGUn2HBsBOKCmd8xbFx8LlZ-oDilMN4Xyz_T4Mb7sA2pcGNb3D3RXH8uroqlS1SsKAZK5-xN54ZE7w7vGbv7_u12-bO8-fXjenl1U3qhxLbkhsvadZg73WhopQSqnXSdWq9bL50y2kippCcwxlCruFpnoRRaopdK8TN2sZ_7EKfHHaWt3YTkacgWadolqwxwVQPP4McXYD_t4pi9WVRCGAUoIFO4p3zeNkXq7MM-AYtg51Rtb3Oqdk7VgrE51az5cJi8W2-oPSoOMWbg0wFwybuhi270IR05rWupa525L3uOcmBPgaJNPtDoqQ2R_Na2U_ivja8v1H4IY8gf_qVnSsdtbaot2NV8_vn6kDdHnst_LxOl_g</recordid><startdate>20070301</startdate><enddate>20070301</enddate><creator>Hoang, Lani T., BS</creator><creator>Lim, Lyndell L., MBBS, FRANZCO</creator><creator>Walton, R. Christopher, MD</creator><creator>Goldstein, Debra A., MD, FRCS(C)</creator><creator>Chalmers, Brent, MD</creator><creator>Rosenbaum, James T., MD</creator><general>Elsevier Inc</general><general>Elsevier</general><general>Elsevier Limited</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope></search><sort><creationdate>20070301</creationdate><title>Primary Sclerosing Cholangitis and Uveitis: A Case Series</title><author>Hoang, Lani T., BS ; Lim, Lyndell L., MBBS, FRANZCO ; Walton, R. Christopher, MD ; Goldstein, Debra A., MD, FRCS(C) ; Chalmers, Brent, MD ; Rosenbaum, James T., MD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c464t-39352af1c468780d550e2a5af6bbdc5a69895565ce0999ed636b46454851c5663</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Adult</topic><topic>Bile</topic><topic>Biological and medical sciences</topic><topic>Cholangitis, Sclerosing - complications</topic><topic>Cholangitis, Sclerosing - diagnosis</topic><topic>Chronic Disease</topic><topic>Female</topic><topic>Gastroenterology. Liver. Pancreas. Abdomen</topic><topic>Humans</topic><topic>Inflammatory bowel disease</topic><topic>Liver</topic><topic>Liver. Biliary tract. Portal circulation. Exocrine pancreas</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Miscellaneous</topic><topic>Ophthalmology</topic><topic>Other diseases. Semiology</topic><topic>Recurrence</topic><topic>Retrospective Studies</topic><topic>Transplants & implants</topic><topic>Uvea diseases</topic><topic>Uveitis - complications</topic><topic>Uveitis - diagnosis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hoang, Lani T., BS</creatorcontrib><creatorcontrib>Lim, Lyndell L., MBBS, FRANZCO</creatorcontrib><creatorcontrib>Walton, R. Christopher, MD</creatorcontrib><creatorcontrib>Goldstein, Debra A., MD, FRCS(C)</creatorcontrib><creatorcontrib>Chalmers, Brent, MD</creatorcontrib><creatorcontrib>Rosenbaum, James T., MD</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>American journal of ophthalmology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hoang, Lani T., BS</au><au>Lim, Lyndell L., MBBS, FRANZCO</au><au>Walton, R. Christopher, MD</au><au>Goldstein, Debra A., MD, FRCS(C)</au><au>Chalmers, Brent, MD</au><au>Rosenbaum, James T., MD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Primary Sclerosing Cholangitis and Uveitis: A Case Series</atitle><jtitle>American journal of ophthalmology</jtitle><addtitle>Am J Ophthalmol</addtitle><date>2007-03-01</date><risdate>2007</risdate><volume>143</volume><issue>3</issue><spage>534</spage><epage>536</epage><pages>534-536</pages><issn>0002-9394</issn><eissn>1879-1891</eissn><coden>AJOPAA</coden><abstract>Purpose To report the cases of six patients with primary sclerosing cholangitis and uveitis. Design Retrospective observational case series. Methods Two index cases were identified from the Uveitis Clinic of the Casey Eye Institute, Oregon Health and Science University and another from the Portland area. Additional cases were identified through a web-based survey of members of the American Uveitis Society. Results Three males and three females were identified. Five of six patients were diagnosed with uveitis prior to primary sclerosing cholangitis. Four had unilateral eye involvement. Five had insidious onset. All had persistent duration. Clinical course was chronic for three, recurrent for two, and chronic-recurrent in one. Vitreous inflammation was prominent in five. Conclusions Although the number of patients who were studied is limited, there appears to be an association between primary sclerosing cholangitis and uveitis. Further studies are required to confirm such an association.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>17317411</pmid><doi>10.1016/j.ajo.2006.09.055</doi><tpages>3</tpages></addata></record> |
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subjects | Adult Bile Biological and medical sciences Cholangitis, Sclerosing - complications Cholangitis, Sclerosing - diagnosis Chronic Disease Female Gastroenterology. Liver. Pancreas. Abdomen Humans Inflammatory bowel disease Liver Liver. Biliary tract. Portal circulation. Exocrine pancreas Male Medical sciences Middle Aged Miscellaneous Ophthalmology Other diseases. Semiology Recurrence Retrospective Studies Transplants & implants Uvea diseases Uveitis - complications Uveitis - diagnosis |
title | Primary Sclerosing Cholangitis and Uveitis: A Case Series |
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