No Association of Polymorphisms in the 5' Region of the CD14 Gene and Food Allergy in a Japanese Population
The gene encoding CD14 is a positional candidate gene for allergic diseases as it is localized on chromosome 5q31, a region that is linked to atopy-related phenotypes. Although it has been shown that a polymorphism in the 5' region of the CD14 gene is associated with food allergy in white subje...
Gespeichert in:
| Veröffentlicht in: | Allergology international 2007, Vol.56 (1), p.23-27 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 27 |
|---|---|
| container_issue | 1 |
| container_start_page | 23 |
| container_title | Allergology international |
| container_volume | 56 |
| creator | Campos, Eduardo Shimojo, Naoki Inoue, Yuzaburo Arima, Takayasu Suzuki, Shuichi Tomiita, Minako Matsuura, Tomoko Hata, Akira Suzuki, Yoichi Aoyagi, Masahiko Kohno, Yoichi |
| description | The gene encoding CD14 is a positional candidate gene for allergic diseases as it is localized on chromosome 5q31, a region that is linked to atopy-related phenotypes.
Although it has been shown that a polymorphism in the 5' region of the CD14 gene is associated with food allergy in white subjects, it is not clear whether this association is also present in the Japanese population.
Eighty-eight children with food allergy were recruited along with 101 children controls without food allergy. DNA samples from these subjects were genotyped by PCR-based restriction fragment length polymorphism (RFLP) assay to investigate the relationship between two polymorphisms in the 5' region of the CD14 gene (C-159T and C-550T) and food allergy.
There was no association among the CD14 alleles, dominant model or recessive model of either polymorphism with food allergy.
The CD14-159 and -550 polymorphisms might not play a major role in the pathogenesis of food allergy in Japanese children. |
| doi_str_mv | 10.2332/allergolint.O-06-432 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_69034496</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S1323893015308443</els_id><sourcerecordid>69034496</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4422-8f0e51ade4945b2ef83069d3f03a78cdfaa96264d115a0c6e14311eda247860f3</originalsourceid><addsrcrecordid>eNqFkU1rGzEQhkVoiB03_yAUnZrTJvparXQpGDefmDiU9iwUaTZRu7vaSuuA_33WsaE9JacZhud9Z5gXoVNKzhnn7MI2DaSn2IRuOF8VRBaCswM0pUKQgpaafRp7znihNCcTdJzzb0Ioq3R1hCa0YqVWRE7Rn_uI5zlHF-wQYodjjR9is2lj6p9DbjMOHR6eAZdn-Ac87YntYPGdCnwNHWDbeXwVo8fzt4s2W4nFd7a3HWQY7fp182b-GR3Wtslwsq8z9Ovq8ufipliurm8X82XhhGCsUDWBkloPQovykUGtOJHa85pwWynna2u1ZFJ4SktLnAQqOKXgLROVkqTmM_R159un-HcNeTBtyA6aZjworrORmnAhtPwQpFopzis1gmIHuhRzTlCbPoXWpo2hxGzTMP-lYVaGSDOmMcq-7P3Xjy34f6L9-0fg2w6A8R0vAZLJLkDnwIcEbjA-hvc3vAIZLZ4f</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>19883378</pqid></control><display><type>article</type><title>No Association of Polymorphisms in the 5' Region of the CD14 Gene and Food Allergy in a Japanese Population</title><source>J-STAGE Free</source><source>MEDLINE</source><source>DOAJ Directory of Open Access Journals</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>Open Access Titles of Japan</source><creator>Campos, Eduardo ; Shimojo, Naoki ; Inoue, Yuzaburo ; Arima, Takayasu ; Suzuki, Shuichi ; Tomiita, Minako ; Matsuura, Tomoko ; Hata, Akira ; Suzuki, Yoichi ; Aoyagi, Masahiko ; Kohno, Yoichi</creator><creatorcontrib>Campos, Eduardo ; Shimojo, Naoki ; Inoue, Yuzaburo ; Arima, Takayasu ; Suzuki, Shuichi ; Tomiita, Minako ; Matsuura, Tomoko ; Hata, Akira ; Suzuki, Yoichi ; Aoyagi, Masahiko ; Kohno, Yoichi</creatorcontrib><description>The gene encoding CD14 is a positional candidate gene for allergic diseases as it is localized on chromosome 5q31, a region that is linked to atopy-related phenotypes.
Although it has been shown that a polymorphism in the 5' region of the CD14 gene is associated with food allergy in white subjects, it is not clear whether this association is also present in the Japanese population.
Eighty-eight children with food allergy were recruited along with 101 children controls without food allergy. DNA samples from these subjects were genotyped by PCR-based restriction fragment length polymorphism (RFLP) assay to investigate the relationship between two polymorphisms in the 5' region of the CD14 gene (C-159T and C-550T) and food allergy.
There was no association among the CD14 alleles, dominant model or recessive model of either polymorphism with food allergy.
The CD14-159 and -550 polymorphisms might not play a major role in the pathogenesis of food allergy in Japanese children.</description><identifier>ISSN: 1323-8930</identifier><identifier>EISSN: 1440-1592</identifier><identifier>DOI: 10.2332/allergolint.O-06-432</identifier><identifier>PMID: 17259806</identifier><language>eng</language><publisher>England: Elsevier B.V</publisher><subject>5' region ; CD14 ; Female ; food allergy ; Food Hypersensitivity - blood ; Food Hypersensitivity - genetics ; gene ; Genetic Predisposition to Disease ; Humans ; Immunoglobulin E - blood ; Japan ; Lipopolysaccharide Receptors - genetics ; Male ; Polymerase Chain Reaction ; polymorphism ; Polymorphism, Restriction Fragment Length</subject><ispartof>Allergology international, 2007, Vol.56 (1), p.23-27</ispartof><rights>2007 Japanese Society of Allergology</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4422-8f0e51ade4945b2ef83069d3f03a78cdfaa96264d115a0c6e14311eda247860f3</citedby><cites>FETCH-LOGICAL-c4422-8f0e51ade4945b2ef83069d3f03a78cdfaa96264d115a0c6e14311eda247860f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,778,782,862,4012,27906,27907,27908</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17259806$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Campos, Eduardo</creatorcontrib><creatorcontrib>Shimojo, Naoki</creatorcontrib><creatorcontrib>Inoue, Yuzaburo</creatorcontrib><creatorcontrib>Arima, Takayasu</creatorcontrib><creatorcontrib>Suzuki, Shuichi</creatorcontrib><creatorcontrib>Tomiita, Minako</creatorcontrib><creatorcontrib>Matsuura, Tomoko</creatorcontrib><creatorcontrib>Hata, Akira</creatorcontrib><creatorcontrib>Suzuki, Yoichi</creatorcontrib><creatorcontrib>Aoyagi, Masahiko</creatorcontrib><creatorcontrib>Kohno, Yoichi</creatorcontrib><title>No Association of Polymorphisms in the 5' Region of the CD14 Gene and Food Allergy in a Japanese Population</title><title>Allergology international</title><addtitle>Allergol Int</addtitle><description>The gene encoding CD14 is a positional candidate gene for allergic diseases as it is localized on chromosome 5q31, a region that is linked to atopy-related phenotypes.
Although it has been shown that a polymorphism in the 5' region of the CD14 gene is associated with food allergy in white subjects, it is not clear whether this association is also present in the Japanese population.
Eighty-eight children with food allergy were recruited along with 101 children controls without food allergy. DNA samples from these subjects were genotyped by PCR-based restriction fragment length polymorphism (RFLP) assay to investigate the relationship between two polymorphisms in the 5' region of the CD14 gene (C-159T and C-550T) and food allergy.
There was no association among the CD14 alleles, dominant model or recessive model of either polymorphism with food allergy.
The CD14-159 and -550 polymorphisms might not play a major role in the pathogenesis of food allergy in Japanese children.</description><subject>5' region</subject><subject>CD14</subject><subject>Female</subject><subject>food allergy</subject><subject>Food Hypersensitivity - blood</subject><subject>Food Hypersensitivity - genetics</subject><subject>gene</subject><subject>Genetic Predisposition to Disease</subject><subject>Humans</subject><subject>Immunoglobulin E - blood</subject><subject>Japan</subject><subject>Lipopolysaccharide Receptors - genetics</subject><subject>Male</subject><subject>Polymerase Chain Reaction</subject><subject>polymorphism</subject><subject>Polymorphism, Restriction Fragment Length</subject><issn>1323-8930</issn><issn>1440-1592</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkU1rGzEQhkVoiB03_yAUnZrTJvparXQpGDefmDiU9iwUaTZRu7vaSuuA_33WsaE9JacZhud9Z5gXoVNKzhnn7MI2DaSn2IRuOF8VRBaCswM0pUKQgpaafRp7znihNCcTdJzzb0Ioq3R1hCa0YqVWRE7Rn_uI5zlHF-wQYodjjR9is2lj6p9DbjMOHR6eAZdn-Ac87YntYPGdCnwNHWDbeXwVo8fzt4s2W4nFd7a3HWQY7fp182b-GR3Wtslwsq8z9Ovq8ufipliurm8X82XhhGCsUDWBkloPQovykUGtOJHa85pwWynna2u1ZFJ4SktLnAQqOKXgLROVkqTmM_R159un-HcNeTBtyA6aZjworrORmnAhtPwQpFopzis1gmIHuhRzTlCbPoXWpo2hxGzTMP-lYVaGSDOmMcq-7P3Xjy34f6L9-0fg2w6A8R0vAZLJLkDnwIcEbjA-hvc3vAIZLZ4f</recordid><startdate>2007</startdate><enddate>2007</enddate><creator>Campos, Eduardo</creator><creator>Shimojo, Naoki</creator><creator>Inoue, Yuzaburo</creator><creator>Arima, Takayasu</creator><creator>Suzuki, Shuichi</creator><creator>Tomiita, Minako</creator><creator>Matsuura, Tomoko</creator><creator>Hata, Akira</creator><creator>Suzuki, Yoichi</creator><creator>Aoyagi, Masahiko</creator><creator>Kohno, Yoichi</creator><general>Elsevier B.V</general><scope>6I.</scope><scope>AAFTH</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>8FD</scope><scope>FR3</scope><scope>H94</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope></search><sort><creationdate>2007</creationdate><title>No Association of Polymorphisms in the 5' Region of the CD14 Gene and Food Allergy in a Japanese Population</title><author>Campos, Eduardo ; Shimojo, Naoki ; Inoue, Yuzaburo ; Arima, Takayasu ; Suzuki, Shuichi ; Tomiita, Minako ; Matsuura, Tomoko ; Hata, Akira ; Suzuki, Yoichi ; Aoyagi, Masahiko ; Kohno, Yoichi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4422-8f0e51ade4945b2ef83069d3f03a78cdfaa96264d115a0c6e14311eda247860f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>5' region</topic><topic>CD14</topic><topic>Female</topic><topic>food allergy</topic><topic>Food Hypersensitivity - blood</topic><topic>Food Hypersensitivity - genetics</topic><topic>gene</topic><topic>Genetic Predisposition to Disease</topic><topic>Humans</topic><topic>Immunoglobulin E - blood</topic><topic>Japan</topic><topic>Lipopolysaccharide Receptors - genetics</topic><topic>Male</topic><topic>Polymerase Chain Reaction</topic><topic>polymorphism</topic><topic>Polymorphism, Restriction Fragment Length</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Campos, Eduardo</creatorcontrib><creatorcontrib>Shimojo, Naoki</creatorcontrib><creatorcontrib>Inoue, Yuzaburo</creatorcontrib><creatorcontrib>Arima, Takayasu</creatorcontrib><creatorcontrib>Suzuki, Shuichi</creatorcontrib><creatorcontrib>Tomiita, Minako</creatorcontrib><creatorcontrib>Matsuura, Tomoko</creatorcontrib><creatorcontrib>Hata, Akira</creatorcontrib><creatorcontrib>Suzuki, Yoichi</creatorcontrib><creatorcontrib>Aoyagi, Masahiko</creatorcontrib><creatorcontrib>Kohno, Yoichi</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Allergology international</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Campos, Eduardo</au><au>Shimojo, Naoki</au><au>Inoue, Yuzaburo</au><au>Arima, Takayasu</au><au>Suzuki, Shuichi</au><au>Tomiita, Minako</au><au>Matsuura, Tomoko</au><au>Hata, Akira</au><au>Suzuki, Yoichi</au><au>Aoyagi, Masahiko</au><au>Kohno, Yoichi</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>No Association of Polymorphisms in the 5' Region of the CD14 Gene and Food Allergy in a Japanese Population</atitle><jtitle>Allergology international</jtitle><addtitle>Allergol Int</addtitle><date>2007</date><risdate>2007</risdate><volume>56</volume><issue>1</issue><spage>23</spage><epage>27</epage><pages>23-27</pages><issn>1323-8930</issn><eissn>1440-1592</eissn><abstract>The gene encoding CD14 is a positional candidate gene for allergic diseases as it is localized on chromosome 5q31, a region that is linked to atopy-related phenotypes.
Although it has been shown that a polymorphism in the 5' region of the CD14 gene is associated with food allergy in white subjects, it is not clear whether this association is also present in the Japanese population.
Eighty-eight children with food allergy were recruited along with 101 children controls without food allergy. DNA samples from these subjects were genotyped by PCR-based restriction fragment length polymorphism (RFLP) assay to investigate the relationship between two polymorphisms in the 5' region of the CD14 gene (C-159T and C-550T) and food allergy.
There was no association among the CD14 alleles, dominant model or recessive model of either polymorphism with food allergy.
The CD14-159 and -550 polymorphisms might not play a major role in the pathogenesis of food allergy in Japanese children.</abstract><cop>England</cop><pub>Elsevier B.V</pub><pmid>17259806</pmid><doi>10.2332/allergolint.O-06-432</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1323-8930 |
| ispartof | Allergology international, 2007, Vol.56 (1), p.23-27 |
| issn | 1323-8930 1440-1592 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_69034496 |
| source | J-STAGE Free; MEDLINE; DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Open Access Titles of Japan |
| subjects | 5' region CD14 Female food allergy Food Hypersensitivity - blood Food Hypersensitivity - genetics gene Genetic Predisposition to Disease Humans Immunoglobulin E - blood Japan Lipopolysaccharide Receptors - genetics Male Polymerase Chain Reaction polymorphism Polymorphism, Restriction Fragment Length |
| title | No Association of Polymorphisms in the 5' Region of the CD14 Gene and Food Allergy in a Japanese Population |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-16T20%3A29%3A24IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=No%20Association%20of%20Polymorphisms%20in%20the%205'%20Region%20of%20the%20CD14%20Gene%20and%20Food%20Allergy%20in%20a%20Japanese%20Population&rft.jtitle=Allergology%20international&rft.au=Campos,%20Eduardo&rft.date=2007&rft.volume=56&rft.issue=1&rft.spage=23&rft.epage=27&rft.pages=23-27&rft.issn=1323-8930&rft.eissn=1440-1592&rft_id=info:doi/10.2332/allergolint.O-06-432&rft_dat=%3Cproquest_cross%3E69034496%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=19883378&rft_id=info:pmid/17259806&rft_els_id=S1323893015308443&rfr_iscdi=true |