Different cerebral cortical areas influence the effect of subthalamic nucleus stimulation on parkinsonian motor deficits and freezing of gait

Inconsistent response in freezing of gait (FOG) with levodopa treatment or STN DBS makes the pathogenesis difficult to understand. We studied brain areas associated with the expression of STN DBS effect on parkinsonian motor deficits and FOG. Ten Parkinson's disease patients with typical FOG we...

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Veröffentlicht in:	Movement disorders 2007-11, Vol.22 (15), p.2176-2182
Hauptverfasser:	Lyoo, Chul Hyoung, Aalto, Sargo, Rinne, Juha O, Lee, Ki Ook, Oh, Seung Hun, Chang, Jin Woo, Lee, Myung Sik
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Antiparkinson Agents - therapeutic use Biological and medical sciences Brain Mapping Cerebral Cortex - cytology Cerebral Cortex - diagnostic imaging Cerebral Cortex - physiology Combined Modality Therapy Deep Brain Stimulation Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Female Fluorodeoxyglucose F18 Gait Disorders, Neurologic - diagnostic imaging Gait Disorders, Neurologic - drug therapy Gait Disorders, Neurologic - physiopathology gait freezing Humans Levodopa - therapeutic use Male Medical sciences Middle Aged Neural Pathways Neurology Parkinson's disease Parkinsonian Disorders - diagnostic imaging Parkinsonian Disorders - drug therapy Parkinsonian Disorders - physiopathology Positron-Emission Tomography Radiopharmaceuticals Subthalamic Nucleus - cytology Subthalamic Nucleus - diagnostic imaging Subthalamic Nucleus - physiology Vascular diseases and vascular malformations of the nervous system
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