Results of Smoking Cessation Therapy in a Specialist Unit

The aim of this study was to assess the results of smoking cessation therapy in a specialist unit by calculating the probability of continued abstinence at 6-month follow-up and analyzing differences according to the characteristics of the individuals. A prospective longitudinal study was undertaken...

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Veröffentlicht in:Archivos de bronconeumología (English ed.) 2007-12, Vol.43 (12), p.669-673
Hauptverfasser: Nerín, Isabel, Novella, Pilar, Belmonte, Asunción, Gargallo, Pilar, Jiménez-Muro, Adriana, Marqueta, Adriana
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Sprache:eng ; spa
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Zusammenfassung:The aim of this study was to assess the results of smoking cessation therapy in a specialist unit by calculating the probability of continued abstinence at 6-month follow-up and analyzing differences according to the characteristics of the individuals. A prospective longitudinal study was undertaken in smokers who received multicomponent smoking-cessation therapy over a period of 3 months. Continued abstinence was assessed on the basis of self-report by participants and confirmed by measurement of exhaled carbon monoxide levels. Kaplan-Meier survival analysis was performed to assess the probability of continued abstinence. Log-rank tests were used to analyze differences in continued abstinence according to different qualitative variables. The 1120 patients who participated in the study (56%men and 44%women) had a mean (SD) age of 44.1 (9.5) years. The mean score on the Fagerström test was 6.3 (2.1).Nicotine replacement therapy was provided in 70.8%of patients while 29.2%received bupropion. The probability of continued abstinence at 6 months was 62.2%. Individuals with a high dependence had a lower probability of continued abstinence at 6 months, as did those in whom treatment adherence was poor. No differences were observed in the probability of abstinence according to sex or type of pharmacological treatment. Individuals with a high nicotine dependence can benefit from intensive smoking-cessation treatment in a specialist unit to achieve continued abstinence. Valorar los resultados del tratamiento del tabaquismo en una unidad especializada, mediante el cálculo de la probabilidad de permanecer abstinente a los 6 meses del seguimiento, y analizar las diferencias existentes según las características de los individuos. Se ha realizado un estudio analítico prospectivo y longitudinal entre los fumadores que recibieron tratamiento multicomponente durante 3 meses. Se consideró la abstinencia continuada mediante la declaración de los propios participantes, confirmada con cooximetría. Se realizó un análisis de supervivencia por el método de Kaplan-Meier. Se aplicaron contrastes de rangos logarítmicos para estudiar las diferencias en la abstinencia continuada de los pacientes para las distintas categorías de las variables cualitativas. Se estudió a 1.120 pacientes (un 56%varones y el 44%mujeres), con una edad media (±desviación estándar de 44,1 ±9,5 años. La puntuación del test de Fagerström fue de 6,3 ±2,1 puntos. El 70,8%recibió tratamiento sustitutivo con nicotin
ISSN:1579-2129
0300-2896
1579-2129
DOI:10.1016/S1579-2129(07)60153-0