Simultaneous quantitation of rosuvastatin and gemfibrozil in human plasma by high-performance liquid chromatography and its application to a pharmacokinetic study

A simple, sensitive and specific high‐performance liquid chromatography method is described for simultaneous determination of rosuvastatin (RST) and gemfibrozil (GFZ) in human plasma using celecoxib as an internal standard (IS). The assay procedure involved extraction of RST, GFZ and IS from plasma...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biomedical chromatography 2006-11, Vol.20 (11), p.1252-1259
Hauptverfasser:	Vittal, Shivva, Shitut, Nikhil R., Kumar, Thammera Ranjit, Vinu, Menon C. A., Mullangi, Ramesh, Srinivas, Nuggehally R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Chromatography, High Pressure Liquid - methods Drug Stability Fluorobenzenes - blood Fluorobenzenes - pharmacokinetics gemfibrozil Gemfibrozil - blood Gemfibrozil - pharmacokinetics HPLC human plasma Humans method validation pharmacokinetics Pyrimidines - blood Pyrimidines - pharmacokinetics Rats Reproducibility of Results rosuvastatin Rosuvastatin Calcium Sensitivity and Specificity Sulfonamides - blood Sulfonamides - pharmacokinetics Ultraviolet Rays
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!