Association between intronic SNP in urate-anion exchanger gene, SLC22A12, and serum uric acid levels in Japanese

Serum uric acid levels are maintained by urate synthesis and excretion. URAT1 (coded by SLC22CA12) was recently proposed to be the major absorptive urate transporter protein in the kidney regulating blood urate levels. Because genetic background is known to affect serum urate levels, we hypothesized...

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Veröffentlicht in:	Life sciences (1973) 2006-11, Vol.79 (23), p.2234-2237
Hauptverfasser:	Shima, Yukio, Teruya, Koji, Ohta, Hidehiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Asian Continental Ancestry Group Creatinine - blood DNA Mutational Analysis - methods Female Genetic Predisposition to Disease Genotype Gout - blood Gout - genetics Humans Hyperuricemia - blood Hyperuricemia - genetics Japan Male Middle Aged Organic Anion Transporters - genetics Organic Cation Transport Proteins - genetics Polymorphism, Single Nucleotide Predictive Value of Tests Serum uric acid Sex Factors Single nucleotide polymorphism URAT1 Urate-anion exchanger Uric Acid - blood
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