Long-term Follow-up of Intacs for Post-LASIK Corneal Ectasia
To report long-term follow-up of Intacs microthin prescription inserts for the management of post-LASIK corneal ectasia. Long-term (5 years), retrospective, nonrandomized study. Eight eyes of 5 patients with post-LASIK corneal ectasia (3 men and 2 women) ages 31 to 54 years (mean age±standard deviat...
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| Veröffentlicht in: | Ophthalmology (Rochester, Minn.) Minn.), 2006-11, Vol.113 (11), p.1909-1917 |
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| creator | Kymionis, George D. Tsiklis, Nikolaos S. Pallikaris, Aristofanis I. Kounis, George Diakonis, Vasilios F. Astyrakakis, Nikolaos Siganos, Charalambos S. |
| description | To report long-term follow-up of Intacs microthin prescription inserts for the management of post-LASIK corneal ectasia.
Long-term (5 years), retrospective, nonrandomized study.
Eight eyes of 5 patients with post-LASIK corneal ectasia (3 men and 2 women) ages 31 to 54 years (mean age±standard deviation [SD], 41.60±9.24 years) who had completed 5 years of follow-up (mean follow-up ± SD, 60.1±4.9 months; range, 57–68 months).
Two Intacs segments, inserted in the usual fashion, were used for low myopia correction (1 each nasally and temporally), with thickness based on the residual refraction of the patients.
Manifest refraction, uncorrected and best spectacle-corrected visual acuity, patient satisfaction, topography, and confocal microscopy analysis.
No intraoperative or late postoperative complications occurred in this series of patients. At 5 years, the SE error was statistically significantly reduced (pre-Intacs mean±SD, −5.47±2.66 diopters [D]; range, −11.50 to −3.00 D) to −2.56±3.44 D (range, −9.50 to 1.5 D;
P = 0.01). At the end of the first postoperative year, refractive stability was obtained and remained stable during the follow-up period with no significant changes between the interval meantime (
P>0.05). Pre-Intacs uncorrected visual acuity was 20/100 or worse in all eyes (range, counting fingers–20/100), whereas at the last follow-up examination, 6 (75%) of 8 eyes had uncorrected visual acuity of 20/40 or better (range, counting fingers–20/25). Two eyes (25%) maintained the pre-Intacs best spectacle-corrected visual acuity, whereas the rest of the eyes (6 eyes; 75%) experienced a gain of 1 or 2 lines. At the end of the first postoperative year, uncorrected and best-spectacle corrected visual acuity and topographic stability were obtained and were shown to have remained stable during the follow-up period with no significant changes between the interval meantime. Lamellar channel deposits were observed in confocal microscopy at or adjacent to the intrastromal ring segment.
Refractive stability was maintained for up to 5 years in the treatment of post-LASIK corneal ectasia after Intacs implantation. There was no evidence of progressive time-dependent corneal ectasia, late regression, or sight-threatening complications in this study. |
| doi_str_mv | 10.1016/j.ophtha.2006.05.043 |
| format | Article |
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Long-term (5 years), retrospective, nonrandomized study.
Eight eyes of 5 patients with post-LASIK corneal ectasia (3 men and 2 women) ages 31 to 54 years (mean age±standard deviation [SD], 41.60±9.24 years) who had completed 5 years of follow-up (mean follow-up ± SD, 60.1±4.9 months; range, 57–68 months).
Two Intacs segments, inserted in the usual fashion, were used for low myopia correction (1 each nasally and temporally), with thickness based on the residual refraction of the patients.
Manifest refraction, uncorrected and best spectacle-corrected visual acuity, patient satisfaction, topography, and confocal microscopy analysis.
No intraoperative or late postoperative complications occurred in this series of patients. At 5 years, the SE error was statistically significantly reduced (pre-Intacs mean±SD, −5.47±2.66 diopters [D]; range, −11.50 to −3.00 D) to −2.56±3.44 D (range, −9.50 to 1.5 D;
P = 0.01). At the end of the first postoperative year, refractive stability was obtained and remained stable during the follow-up period with no significant changes between the interval meantime (
P>0.05). Pre-Intacs uncorrected visual acuity was 20/100 or worse in all eyes (range, counting fingers–20/100), whereas at the last follow-up examination, 6 (75%) of 8 eyes had uncorrected visual acuity of 20/40 or better (range, counting fingers–20/25). Two eyes (25%) maintained the pre-Intacs best spectacle-corrected visual acuity, whereas the rest of the eyes (6 eyes; 75%) experienced a gain of 1 or 2 lines. At the end of the first postoperative year, uncorrected and best-spectacle corrected visual acuity and topographic stability were obtained and were shown to have remained stable during the follow-up period with no significant changes between the interval meantime. Lamellar channel deposits were observed in confocal microscopy at or adjacent to the intrastromal ring segment.
Refractive stability was maintained for up to 5 years in the treatment of post-LASIK corneal ectasia after Intacs implantation. There was no evidence of progressive time-dependent corneal ectasia, late regression, or sight-threatening complications in this study.</description><identifier>ISSN: 0161-6420</identifier><identifier>EISSN: 1549-4713</identifier><identifier>DOI: 10.1016/j.ophtha.2006.05.043</identifier><identifier>PMID: 17074560</identifier><identifier>CODEN: OPHTDG</identifier><language>eng</language><publisher>New York, NY: Elsevier Inc</publisher><subject>Adult ; Biological and medical sciences ; Corneal Diseases - diagnosis ; Corneal Diseases - etiology ; Corneal Diseases - physiopathology ; Corneal Diseases - surgery ; Corneal Topography ; Dilatation, Pathologic ; Eyeglasses ; Female ; Follow-Up Studies ; Humans ; Keratomileusis, Laser In Situ - adverse effects ; Male ; Medical sciences ; Microscopy, Confocal ; Middle Aged ; Miscellaneous ; Ophthalmology ; Patient Satisfaction ; Postoperative Complications ; Postoperative Period ; Prostheses and Implants - adverse effects ; Refraction, Ocular ; Retrospective Studies ; Surveys and Questionnaires ; Visual Acuity</subject><ispartof>Ophthalmology (Rochester, Minn.), 2006-11, Vol.113 (11), p.1909-1917</ispartof><rights>2006 American Academy of Ophthalmology</rights><rights>2006 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c390t-4fda820607a9630488602e65901d0f5b6bb5f1d8e073e0df0c7f69279b12c3bd3</citedby><cites>FETCH-LOGICAL-c390t-4fda820607a9630488602e65901d0f5b6bb5f1d8e073e0df0c7f69279b12c3bd3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0161642006007299$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=18245107$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17074560$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kymionis, George D.</creatorcontrib><creatorcontrib>Tsiklis, Nikolaos S.</creatorcontrib><creatorcontrib>Pallikaris, Aristofanis I.</creatorcontrib><creatorcontrib>Kounis, George</creatorcontrib><creatorcontrib>Diakonis, Vasilios F.</creatorcontrib><creatorcontrib>Astyrakakis, Nikolaos</creatorcontrib><creatorcontrib>Siganos, Charalambos S.</creatorcontrib><title>Long-term Follow-up of Intacs for Post-LASIK Corneal Ectasia</title><title>Ophthalmology (Rochester, Minn.)</title><addtitle>Ophthalmology</addtitle><description>To report long-term follow-up of Intacs microthin prescription inserts for the management of post-LASIK corneal ectasia.
Long-term (5 years), retrospective, nonrandomized study.
Eight eyes of 5 patients with post-LASIK corneal ectasia (3 men and 2 women) ages 31 to 54 years (mean age±standard deviation [SD], 41.60±9.24 years) who had completed 5 years of follow-up (mean follow-up ± SD, 60.1±4.9 months; range, 57–68 months).
Two Intacs segments, inserted in the usual fashion, were used for low myopia correction (1 each nasally and temporally), with thickness based on the residual refraction of the patients.
Manifest refraction, uncorrected and best spectacle-corrected visual acuity, patient satisfaction, topography, and confocal microscopy analysis.
No intraoperative or late postoperative complications occurred in this series of patients. At 5 years, the SE error was statistically significantly reduced (pre-Intacs mean±SD, −5.47±2.66 diopters [D]; range, −11.50 to −3.00 D) to −2.56±3.44 D (range, −9.50 to 1.5 D;
P = 0.01). At the end of the first postoperative year, refractive stability was obtained and remained stable during the follow-up period with no significant changes between the interval meantime (
P>0.05). Pre-Intacs uncorrected visual acuity was 20/100 or worse in all eyes (range, counting fingers–20/100), whereas at the last follow-up examination, 6 (75%) of 8 eyes had uncorrected visual acuity of 20/40 or better (range, counting fingers–20/25). Two eyes (25%) maintained the pre-Intacs best spectacle-corrected visual acuity, whereas the rest of the eyes (6 eyes; 75%) experienced a gain of 1 or 2 lines. At the end of the first postoperative year, uncorrected and best-spectacle corrected visual acuity and topographic stability were obtained and were shown to have remained stable during the follow-up period with no significant changes between the interval meantime. Lamellar channel deposits were observed in confocal microscopy at or adjacent to the intrastromal ring segment.
Refractive stability was maintained for up to 5 years in the treatment of post-LASIK corneal ectasia after Intacs implantation. There was no evidence of progressive time-dependent corneal ectasia, late regression, or sight-threatening complications in this study.</description><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Corneal Diseases - diagnosis</subject><subject>Corneal Diseases - etiology</subject><subject>Corneal Diseases - physiopathology</subject><subject>Corneal Diseases - surgery</subject><subject>Corneal Topography</subject><subject>Dilatation, Pathologic</subject><subject>Eyeglasses</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Keratomileusis, Laser In Situ - adverse effects</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Microscopy, Confocal</subject><subject>Middle Aged</subject><subject>Miscellaneous</subject><subject>Ophthalmology</subject><subject>Patient Satisfaction</subject><subject>Postoperative Complications</subject><subject>Postoperative Period</subject><subject>Prostheses and Implants - adverse effects</subject><subject>Refraction, Ocular</subject><subject>Retrospective Studies</subject><subject>Surveys and Questionnaires</subject><subject>Visual Acuity</subject><issn>0161-6420</issn><issn>1549-4713</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp90M9LwzAUwPEgipvT_0CkF721vvxo2oIIY2w6LCio55CmiXZ0zUxSxf_ejg128_Qun_d4fBG6xJBgwPx2ldjNZ_iUCQHgCaQJMHqExjhlRcwyTI_ReGA45ozACJ15v4IBcspO0QhnkLGUwxjdlbb7iIN262hh29b-xP0msiZadkEqHxnrohfrQ1xOX5dP0cy6Tss2mqsgfSPP0YmRrdcX-zlB74v52-wxLp8flrNpGStaQIiZqWVOgEMmC06B5TkHonlaAK7BpBWvqtTgOteQUQ21AZUZXpCsqDBRtKrpBN3s7m6c_eq1D2LdeKXbVnba9l7wAgjFhA6Q7aBy1nunjdi4Zi3dr8AgttXESuyqiW01AakYqg1rV_v7fbXW9WFpn2kA13sgvZKtcbJTjT-4nLAUD99P0P3O6aHGd6Od8KrRndJ147QKorbN_5_8AYHoih4</recordid><startdate>20061101</startdate><enddate>20061101</enddate><creator>Kymionis, George D.</creator><creator>Tsiklis, Nikolaos S.</creator><creator>Pallikaris, Aristofanis I.</creator><creator>Kounis, George</creator><creator>Diakonis, Vasilios F.</creator><creator>Astyrakakis, Nikolaos</creator><creator>Siganos, Charalambos S.</creator><general>Elsevier Inc</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20061101</creationdate><title>Long-term Follow-up of Intacs for Post-LASIK Corneal Ectasia</title><author>Kymionis, George D. ; Tsiklis, Nikolaos S. ; Pallikaris, Aristofanis I. ; Kounis, George ; Diakonis, Vasilios F. ; Astyrakakis, Nikolaos ; Siganos, Charalambos S.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c390t-4fda820607a9630488602e65901d0f5b6bb5f1d8e073e0df0c7f69279b12c3bd3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Corneal Diseases - diagnosis</topic><topic>Corneal Diseases - etiology</topic><topic>Corneal Diseases - physiopathology</topic><topic>Corneal Diseases - surgery</topic><topic>Corneal Topography</topic><topic>Dilatation, Pathologic</topic><topic>Eyeglasses</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Humans</topic><topic>Keratomileusis, Laser In Situ - adverse effects</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Microscopy, Confocal</topic><topic>Middle Aged</topic><topic>Miscellaneous</topic><topic>Ophthalmology</topic><topic>Patient Satisfaction</topic><topic>Postoperative Complications</topic><topic>Postoperative Period</topic><topic>Prostheses and Implants - adverse effects</topic><topic>Refraction, Ocular</topic><topic>Retrospective Studies</topic><topic>Surveys and Questionnaires</topic><topic>Visual Acuity</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kymionis, George D.</creatorcontrib><creatorcontrib>Tsiklis, Nikolaos S.</creatorcontrib><creatorcontrib>Pallikaris, Aristofanis I.</creatorcontrib><creatorcontrib>Kounis, George</creatorcontrib><creatorcontrib>Diakonis, Vasilios F.</creatorcontrib><creatorcontrib>Astyrakakis, Nikolaos</creatorcontrib><creatorcontrib>Siganos, Charalambos S.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Ophthalmology (Rochester, Minn.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kymionis, George D.</au><au>Tsiklis, Nikolaos S.</au><au>Pallikaris, Aristofanis I.</au><au>Kounis, George</au><au>Diakonis, Vasilios F.</au><au>Astyrakakis, Nikolaos</au><au>Siganos, Charalambos S.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Long-term Follow-up of Intacs for Post-LASIK Corneal Ectasia</atitle><jtitle>Ophthalmology (Rochester, Minn.)</jtitle><addtitle>Ophthalmology</addtitle><date>2006-11-01</date><risdate>2006</risdate><volume>113</volume><issue>11</issue><spage>1909</spage><epage>1917</epage><pages>1909-1917</pages><issn>0161-6420</issn><eissn>1549-4713</eissn><coden>OPHTDG</coden><abstract>To report long-term follow-up of Intacs microthin prescription inserts for the management of post-LASIK corneal ectasia.
Long-term (5 years), retrospective, nonrandomized study.
Eight eyes of 5 patients with post-LASIK corneal ectasia (3 men and 2 women) ages 31 to 54 years (mean age±standard deviation [SD], 41.60±9.24 years) who had completed 5 years of follow-up (mean follow-up ± SD, 60.1±4.9 months; range, 57–68 months).
Two Intacs segments, inserted in the usual fashion, were used for low myopia correction (1 each nasally and temporally), with thickness based on the residual refraction of the patients.
Manifest refraction, uncorrected and best spectacle-corrected visual acuity, patient satisfaction, topography, and confocal microscopy analysis.
No intraoperative or late postoperative complications occurred in this series of patients. At 5 years, the SE error was statistically significantly reduced (pre-Intacs mean±SD, −5.47±2.66 diopters [D]; range, −11.50 to −3.00 D) to −2.56±3.44 D (range, −9.50 to 1.5 D;
P = 0.01). At the end of the first postoperative year, refractive stability was obtained and remained stable during the follow-up period with no significant changes between the interval meantime (
P>0.05). Pre-Intacs uncorrected visual acuity was 20/100 or worse in all eyes (range, counting fingers–20/100), whereas at the last follow-up examination, 6 (75%) of 8 eyes had uncorrected visual acuity of 20/40 or better (range, counting fingers–20/25). Two eyes (25%) maintained the pre-Intacs best spectacle-corrected visual acuity, whereas the rest of the eyes (6 eyes; 75%) experienced a gain of 1 or 2 lines. At the end of the first postoperative year, uncorrected and best-spectacle corrected visual acuity and topographic stability were obtained and were shown to have remained stable during the follow-up period with no significant changes between the interval meantime. Lamellar channel deposits were observed in confocal microscopy at or adjacent to the intrastromal ring segment.
Refractive stability was maintained for up to 5 years in the treatment of post-LASIK corneal ectasia after Intacs implantation. There was no evidence of progressive time-dependent corneal ectasia, late regression, or sight-threatening complications in this study.</abstract><cop>New York, NY</cop><pub>Elsevier Inc</pub><pmid>17074560</pmid><doi>10.1016/j.ophtha.2006.05.043</doi><tpages>9</tpages></addata></record> |
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| ispartof | Ophthalmology (Rochester, Minn.), 2006-11, Vol.113 (11), p.1909-1917 |
| issn | 0161-6420 1549-4713 |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Adult Biological and medical sciences Corneal Diseases - diagnosis Corneal Diseases - etiology Corneal Diseases - physiopathology Corneal Diseases - surgery Corneal Topography Dilatation, Pathologic Eyeglasses Female Follow-Up Studies Humans Keratomileusis, Laser In Situ - adverse effects Male Medical sciences Microscopy, Confocal Middle Aged Miscellaneous Ophthalmology Patient Satisfaction Postoperative Complications Postoperative Period Prostheses and Implants - adverse effects Refraction, Ocular Retrospective Studies Surveys and Questionnaires Visual Acuity |
| title | Long-term Follow-up of Intacs for Post-LASIK Corneal Ectasia |
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